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Colorado Pulmonary-Alcohol Research Consortium (CoPARC)


Consortium Research Data

The Translational Informatics function of the Colorado CTSI develops research informatics tools and provides training and support for research informatics needs. To facilitate data sharing between investigators utilizing the consortium, we have employed REDCap, a web-based, HIPAA-compliant study data management solution that is straightforward and robust and being adopted widely by members of the national CTSA consortium. Human subjects data collected as a part of CoPARC investigations will be stored on the REDCap system. The data can be accessed by designated investigators as part of on-going research efforts. Descriptions of the type of data being collected are provided.

1. Data from AUD subjects/control subjects: A detailed screening exam and data collection will be performed in the CTRC, including

  • A full medical history
  • Physical exam
  • Complete blood count, comprehensive chemistry panel, urine toxicology screen, pregnancy test (in women)
  • PA/Lateral chest radiograph
  • Simple spirometry

After screening is complete, AUD subjects will complete

  • Validated alcohol instruments, including the AUDIT, CAGE, and SMAST
  • Quantification and pattern of alcohol drinking questions
  • Smoking history
  • Respiratory symptoms surveys, including the St. George’s Respiratory Questionnaire
  • Exposure questions

2. Data from Burn injured patients. These patients will have a complete assessment as soon as possible after admission, preferably within the first 24 hours. This will include

  • A full medical history, including severity of illness scoring
  • Physical exam
  • Complete blood count and comprehensive chemistry panel, urine toxicology screen, blood alcohol level
  • Chest radiograph

Patients will be monitored daily for changes in their status. After 14 days, outcomes will be assessed in patients including

  • Need for ventilator support
  • Length of time on ventilator, in ICU, and in the hospital
  • Survival
  • Development of pulmonary infection