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  Bifeng Gao, Ph.D.
  Instructor of Medicine  
  University of Colorado Denver

  Pulmonary Sciences & Critical Care Medicine

 

  Bifeng.Gao@ucdenver.edu

 

Education & Training
Xuzhou Normal College, Xuzhou, China 1985 B.S. Chemistry

Nanjing University, Nanjing, China 1988 M.S. Organic Chemistry

Fudan University, Shanghai, China 1988 M.S. Mol Genetics & Biochem

Chinese Academy of Medl Sci, Beijing, China 1990 Ph.D. Mol Genetics & Biochem

PROFESSIONAL EXPERIENCE

1999-present
Director and Manager, Affymetrix Microarray Core laboratory, Cancer Center, UCD, Denver, Colorado

1993-1998
Instructor of medicine (School of Medicine), University of Colorado Denver, Denver, Colorado

1991-1993
Postdoctoral fellow, Webb-Waring Institute, University of Colorado Denver

1988-1990
Research Associate, Peking Union Medical College, Beijing, China

SELECTED PUBLICATIONS

  1. Nomuro I, Ong PY, Gao B, Boguniewicz M, Leung DYM. Differences in gene expression array of superantigen-stimulated cells. J Allergy Clin Immunol. 2002 (In Press)
  2. Robert Mason, B. Gao, Tianli Pan, X. Jiang, M. Eckart, S. Neben, Role of KGF in Regulating Lipogenesis in Alveolar Type II Cells: A Gene Profiling Approach. (Submitted)
  3. Geraci, M.W., Gao, B., Hoshikawa, Y., Yeager, M.E., Tuder, R.M., and Voelkel, N.F. Genomic approaches to research in pulmonary hypertension. Respiratory Research, In Press, 2001.
  4. Jotte, R.M., Spalding, A.C., Sugita, M., Gao, B., Geraci, M.W., Franklin, W., and Johnson, G.L. Lung cancers have an altered TRAIL to apoptosis. Submitted
  5. Geraci, M.W., Shepherd, D.C., Moore, M.D., Vernon, J.D., Gao, B.F., Shannon, J.M., Miller, Y.E. and Voelkel, N.F. Rat prostacyclin synthase: Cloning and regulation of pulmonary mRNA expression in vivo. Submitted.
  6. Bishop, A.E., Mason, N.A., Chacon, M.R., Mikhail, G., Yacoub, M.H., Cool, C.D., Gao, B., Geraci, M.W., Voelkel, N.F., and Polak, J.M. Reduced expression of prostacyclin receptor in primary pulmonary hypertension. Submitted.
  7. Geraci, M.W., Moore, M.D., Gessel, T.L., Yeager, M.E., Alger, L., Golpon, H., Gao, B., Loyd, J.E., Tuder, R.M., and Voelkel, N.F. Gene expression patterns in the lungs of patients with primary pulmonary hypertension – A gene microarray analysis. Circulation Research, 88:555-562, 2001.
  8. Girod, C.E., D.H. Shin, M.W. Geraci, H.B. Warren, L.G. Dobbs, B. Gao, J.S. Rainer, A.K. Bauer, M. Ikegami, J.M. Shannon, and Y.E. Miller. Surfactant protein C promoter-driven expression of T1-alpha induces lung inflammation. Chest 116 (1Suppl):61S, 1999.
  9. Geraci, M.W., Gao, B., Shepherd, D.C., Moore, M.D., Westcott, J.Y., Alger, L.A., Tuder, R.M., and Voelkel, N.F. Selective pulmonary prostacyclin synthase overexpression in transgenic mice protects against the development of hypoxic pulmonary hypertension. J. Clin. Invest. 103:1509-1515, 1999.
  10. Geraci, M.W., Lepley, R.A., Gao, B., Tuder, R.M., and Voelkel, N.F. Analysis of gene expression in severe pulmonary hypertension and normal human lung: insights in to pathogenesis. American Journal of Respiratory and Critical Care Medicine, A696, 1999.
  11. Geraci, M.W., Gao, B., Moore, M.D., Lepley, R.A., Tuder, R.M., and Voelkel, N.F. Microarray analysis of gene expression and proteomics in severe pulmonary hypertension and normal human lung. Circulation, 100:I-241, 1999.
  12. Geraci, M, Gao, B., Shepherd, D, Westcott, J, Tuder, R, and Voelkel, N. Pulmonary prostacyclin synthase overexpression in transgenic mice protects against the development of pulmonary hypertension. American Journal of Respiratory and Critical Care Medicine, 157: A558, 1998.
  13. Gao, B., Flores, S. and McCord, J. Expression, Purification, and Characterization of Second Generation of Superoxide Dismutase (In preparation).
  14. Gao, B. McCord J. (1998). Effects of superoxide dismutases on hypertension in spontaneously hypertensive rats. Free Radicals in Biology and Medicine, 25: S94.
  15. Geraci, MW, Gao, B., Shepherd D, Allard J, Curiel D, Westcott J, and Voelkel N. (1998). Pulmonary prostacyclin synthase overexpression by adenovirus transfection and in transgenic mice. Chest 114: 99S.
  16. Gao, B., Flores, S. and McCord, J. (1996). A novel Escherichia coli vector for oxygen? inducible high level expression of foreign genes. Gene 176: 269?272.
  17. Geraci, M.W., Shepherd, D.C., Moore, M.D., Gao, B., and Voelkel, N.F. (1996). Rat prostacyclin synthase: cloning and regulation of gene expression by steroid hormones and endotoxin. Circulation 94: 3784.
  18. Gao, B., Flores, S. and McCord, J. (1995). A site?directed mutant of Cu/Zn?superoxide dismutase modeled after native extracellular superoxide dismutase. Biological Trace Element Research 47: 95?100.
  19. McCord, J., Gao, B., Leff, J. and Flores, S. (1994). Neutrophil generated free radicals: Possible mechanisms of injury in adult respiratory distress syndrome. Environmental Health Perspectives 102 (Suppl 10): 57?60.
  20. Gao, B., Flores S. and McCord J. (1993). Cloning and characterization of Cu,Zn?SOD variants with altered pharmaceutical properties. FASEB Journal 7: A1066.
  21. Gao, B., Xu, X., Zhao, M. et al. (1990). High?level expression of human Cu/Zn superoxide dismutase in Escherichia coli. Basic Medical Sciences and Clinics 10: 23?26.
  22. Gao, B., Xu, X. et al. (1990). Chemical synthesis and cloning of a gene for human Cu/Zn superoxide dismutase. Basic Medical Sciences and Clinics 10: 39?41.
  23. Gao, B., Min, Y. et al. (1990). Chemical synthesis and cloning of a gene for human calcitonin analogue. Basic Medical Sciences and Clinics 10: 28?31.
  24. Gao, B., Min, Y., Dai, D., Shi, W. and Wang, Q. (1989). Chemical synthesis of oligodeoxynucleotides. Journal of Fudan University (Natural Sciences) 28: 375?379.
  25. Gao, B., Deng, Y., Shi, W., Min, Y. and Wang, Q. (1989).