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Flaig Research Lab

Genitourinary Cancer


Flaig Lab Pic
From left to right: Xiaoping Yang, Thomas Flaig, Lih-Jen Su

Research

Genitourinary Cancer Translational Research

Selected Publications

  • Functionalized gold nanorods for thermal ablation treatment of bladder cancer.  Cho SK, Emoto K, Su LJ, Yang X, Flaig TW, Park W.   J Biomed Nanotechnol. 2014 Jul;10(7):1267-76.   PMID: 24804547
  • Simultaneous activation of Kras and inactivation of p53 induces soft tissue sarcoma and bladder urothelial hyperplasia.   Yang X, La Rosa FG, Genova EE, Huber K, Schaack J, Degregori J, Serkova NJ, Li Y, Su LJ, Kessler E, Flaig TW.  PLoS One. 2013 Sep 18;8(9):e74809. doi: 10.1371/journal.pone.0074809.  PMID: 24058630
  • Diphtheria toxin-epidermal growth factor fusion protein DAB389EGF for the treatment of bladder cancer.  Yang X, Kessler E, Su LJ, Thorburn A, Frankel AE, Li Y, La Rosa FG, Shen J, Li CY, Varella-Garcia M, Glodé LM, Flaig TW.  Clin Cancer Res. 2013 Jan 1;19(1):148-57. doi: 10.1158/1078-0432.CCR-12-1258.  PMID: 23172881
  • miR-125b Regulation of Androgen Receptor Signaling Via Modulation of the Receptor Complex Co-Repressor NCOR2.  Yang X, Bemis L, Su LJ, Gao D, Flaig TW.   Biores Open Access. 2012 Apr;1(2):55-62. doi: 10.1089/biores.2012.9903.  PMID: 23514806
  • Dual epidermal growth factor receptor and vascular endothelial growth factor receptor inhibition with vandetanib sensitizes bladder cancer cells to cisplatin in a dose- and sequence-dependent manner.   Flaig TW, Su LJ, McCoach C, Li Y, Raben D, Varella-Garcia M, Bemis LT.   BJU Int. 2009 Jun;103(12):1729-37. doi: 10.1111/j.1464-410X.2009.08367.x.  PMID: 19220256
  • A study of high-dose oral silybin-phytosome followed by prostatectomy in patients with localized prostate cancer.  Flaig TW, Glodé M, Gustafson D, van Bokhoven A, Tao Y, Wilson S, Su LJ, Li Y, Harrison G, Agarwal R, Crawford ED, Lucia MS, Pollak M.  Prostate. 2010 Jun 1;70(8):848-55. doi: 10.1002/pros.21118.  PMID: 20127732
  • Silibinin synergizes with mitoxantrone to inhibit cell growth and induce apoptosis in human prostate cancer cells.   Flaig TW, Su LJ, Harrison G, Agarwal R, Glodé LM. Int J Cancer. 2007 May 1;120(9):2028-33.   PMID: 17230508