2012
Publications
Christoph DC, Mascaux C, Reyna Asuncion B, Tran C, Lu X, Wynes MW, Gauler TC, Wohlschlaeger J, Theegarten D, Neumann V, Hepp R, Welter S, Stamatis G, Tannapfel A, Schuler M, Eberhardt WEE, Hirsch FR.
Folylpoly-Glutamate Synthetase Expression is associated with Tumor Response and Outcame from Pemetrexed -based Chemotherapy in Malignant Pleural Mesothelioma.
Submitted J Thorac. Oncol
Abstracts
Mascaux C., Keith R., Feser W.J., Lewis M., Baron A.E., Coldren C.D., Merrick D.T., Kennedy T.C., Eckelberger J.I., Franklin W.A., Bunn P.A. Jr, Miller Y.E., Hirsch F.R. Histology and intervention related miRNA expression changes from baseline to follow-up paired bronchial biopsies of patient in the Iloprost chemoprevention trial.
AACR-IASLC joint conference on Molecular Origin of Lung Cancer, San Diego, CA, USA, January 2012, Abstract B16
Mascaux C., Keith R., Feser W.J., Lewis M., Baron A.E., Merrick D.T., Franklin W.A., Bunn P.A. Jr, Miller Y.E., Hirsch F.R.
miR-34c is a potential biomarker for histological response in lung cancer chemoprevention studies.
3nd European Lung Cancer Conference, Geneva, Switzerland, April 2012, Abstract 65O
2011
Publications
Mascaux C. Wynes M.W., Yasufumi K., Tran C., Reyna Asuncion B. Zhao J., Gustavson M., Ranger-Moore J., Gaire F., Matsubayashi J., Nagao T., Yoshida K., Ohira T., Ikeda N., Hirsch F.R.
EGFR protein expression in non-small cell lung cancer predicts response to an EGFR tyrosine kinase inhibitor - A novel antibody for immunohistochemistry or AQUA technology. Clin Cancer Res. 2011 Dec 15;17(24):7796-807. PMID:21994417
Abstracts
Christoph D.C., Mascaux C., Wynes M.W., Reyna Asuncion B., Wohlschlaeger J., Theegarten D., Gauler T.C., Schuler M.H., Eberhardt W.E.E., Hirsch F.R. Predictive value of thymidylate synthase and folylpoly-glutamate synthetase for clinical benefit from pemetrexed in malignant pleural mesothelioma. 14th World Conference on Lung Cancer, Amsterdam, The Netherlands, July 2011, J Thor Oncol (2011), 6 (6) suppl 2, S1092, P2.247.
Mascaux C., Anthoine G., Eckelberger J., Miller Y.E., Kennedy T.C., Keith R.L., Feser W.J., Barón A.E., Haller A., Franklin W., Burny A., Hirsch F.R., Sculier J.P.
Three miRNAs identified for the early detection of squamous cell carcinoma of the lung in one testing cohort and 2 international validation cohorts.
14th Word Conference on Lung Cancer (WCLC), Amsterdam, The Netherlands, July 2011, J Thor Oncol (2011), 6 (6) suppl 2, S298, O06.06.
Mascaux C., Hirsch FR.
Pathways Pathogenesis.
14th Word Conference on Lung Cancer (WCLC), Amsterdam, The Netherlands, July 2011, J Thor Oncol (2011), 6 (6) suppl 2, S58, M01.3.
Wynes M.W., Kato Y., Mascaux C., Reyna Asuncion B.G., Sanchez S.A., Matsubayashi J., Yoshida K., Nagao T., Furukawa K., Ikeda N., Hirsch F.R.
Immunohistochemistry using an EGFR internal domain-specific antibody predicts response and outcome to an EGFR tyrosine kinase inhibitor.
14th World Conference on Lung Cancer, Amsterdam, The Netherlands, July 2011, WCLC proceeding 2011,
J Thor Oncol (2011), 6 (6) suppl 2, S567, MO10.10.
Kato Y., Wynes M.W., Mascaux C., Reyna Asuncion B., Tran C., Yoshida K., Matsubayashi J., Nakajima E., Ohira T., Nagao T., Furukawa K., Ikeda N. Hirsch F.R.
IGF-1R as a predictive marker for EGFR TKI (Gefitinib) resistance in Non Small Cell Lung Cancer using IHC and AQUA technology.
14th World Conference on Lung Cancer, Amsterdam, The Netherlands, July 2011, WCLC proceeding 2011,
J Thor Oncol (2011), 6 (6) suppl 2, S449, O39.03.
Christoph D.C., Mascaux C., Wynes M.W., Reyna Asuncion B., Wohlschlaeger J., Theegarten D., Gauler T.C., Schuler M.H., Eberhardt W.E.E., Hirsch F.R.
Predictive value of thymidylate synthase and folylpoly-glutamate synthetase for clinical benefit from pemetrexed in malignant pleural mesothelioma. 2011 ASCO Annual Meeting, Chicago, IL, USA, June 2011. J Clin Oncol 2011, 29, suppl, abstract 7024.
Merrick D.T., Coldren C.D., Franklin W, Sugita M, Miller Y.E., Keith R.L., Kennedy T.C., Chesnut P., Mascaux C., Hirsch F.R., Geraci M.W., Nemenoff R.
Identification of Alterations in Gene Expression that Distinguish Persistent from Regressive Bronchial Dysplasia.
14th World Conference on Lung Cancer, Amsterdam, The Netherlands, July 2011, WCLC proceeding 2011,
J Thor Oncol (2011), 6 (6) suppl 2, S1097, P2.252.
Kato Y., Mascaux C., Wynes M.W., Reyna Asuncion B., Tran C., Yoshida K., Matsubayashi J., Nakajima E., Ohira T., Nagao T., Furukawa K., Ikeda N. Hirsch F.R.
The role of IGF-1R in EGFR TKI resistance in NSCLC using IHC and AQUA technology.
2011 ASCO Annual Meeting, Chicago, IL, USA, June 2011. J Clin Oncol 2011, 29, suppl, abstract 10556.
Christoph D.C., Mascaux C., Wynes M.W., Reyna Asuncion B., Wohlschlaeger J., Theegarten D., Gauler T.C., Schuler M.H., Eberhardt W.E.E., Hirsch F.R.
Predictive value of thymidylate synthase and folylpoly-glutamate synthetase for clinical benefit from pemetrexed in malignant pleural mesothelioma.
2011 ASCO Annual Meeting, Chicago, IL, USA, June 2011. J Clin Oncol 2011, 29, suppl, abstract 7024.
2010
Publications
Kato Y., Peled N., Wynes M.W., Yoshida K., Pardo M., Mascaux C., Ohira T., Tsubo M., Matsubayashi J., Nagao T., Ikeda N., Hirsch F.R.
Novel EGFR mutation specific antibodies for NSCLC: Immunohistochemistry as a possible screening method for EGFR mutations.
J Thor Oncol, 5 (10), (2010): 1551-8 PMID:20697298
Mascaux C., Peled N., Garg K., Kato Y., Wynes M.W., Hirsch F.R.
Early detection and screening of lung cancer.
Expert Rev Mol Diagn, 10 (6) (2010): 799-815.PMID:20843203
Peled N., Mascaux C., Wynes M.W., Hirsch F.R.
Lung Cancer: A multidisciplinary Approach to Diagnosis and Management. Chapter 21:Role of Personalized Medicine: Now and the Future.
Editors Kernstine K.H. and Reckamp K.L. Publisher: Demos Medical Publishing. 2010.
Abstracts
Wynes M.W., Mascaux C., Kato Y., Reyna-Asuncion B., Zhao J., Powell W., Ranger-Moore J., Yoshida K., Ikeda N., Hirsch F.R.
Prediction of response to Gefitinib in NSCLC by EGFR protein expression is increased by a novel antibody and the use of AQUA technology.
Chicago Multidisciplinary Symposium in Thoracic Oncology, Chicago, USA, December 2010, S504, abstract 10.
Kato Y., Peled N., Yoshida K., Wynes M. W., Pardo M., Mascaux C., Tsuboi M., Ohira T., Ikeda N., Hirsch F.R.
Immunohistochemistry detection of epidermal growth factor receptor (EGFR) exons 19 and 21 mutations in non-small cell lung cancer (NSCLC) using novel mutation specific antibodies.,
2010 ASCO Annual Meeting, Chicago, IL, USA, June 2010, ASCO meeting proceedings 2010, page733s abstract 10542.
Mascaux C., Coldren C., Haibe-Kains B., Anthoine G., Haller H., Ninane V., Burny A., Sculier JP, Hirsch FR.
Different gene expression profiles between current and former smokers in lung squamous carcinogenesis.
AACR-IASLC joint conference on Molecular Origin of Lung Cancer, Coronado, CA, USA, January 2010
AACR-IASLC Scholar-in-Training Award.
Mascaux C., Anthoine G., Peled N., Ninane V., Burny A. Sculier JP, Hirsch FR.
Molecular screening.
2nd European Lung Cancer Conference, Geneva, Switzerland, April 2010, J Thoracic Oncol (2010), 5 (5), S32, abstract 72IN
Mascaux C., Coldren C., Haibe-Kains B., Anthoine G., Haller H., Ninane V., Burny A., Sculier JP, Hirsch FR.
Gene expression differences in current and former smokers in lung squamous preneplasia.
2010 ASCO Annual Meeting, Chicago, IL, USA, June 2010, ASCO meeting proceedings (2010), page741s abstract 10575.
Mascaux C., Coldren C., Haibe-Kains B., Anthoine G., Haller H., Ninane V., Burny A., Sculier JP, Hirsch FR.
Gene expression differences in current and former smokers in lung squamous preneplasia.
2010 Aspen Lung Conference, Aspen, CO, USA, June 2010, Proceedings of the American Thoracic Society, 8 (2011), page 208.