As an undergraduate at the University of Colorado, I started my scientific career focused on basic science research of cancer. In the laboratory of Dr. Min Han, I studied the Ras cell signaling pathway using the C. elegans model organism. In the MD/PhD program at Oregon Heath & Science University, I focused on translational leukemia research. Under the mentorship of Drs. Brian Druker and Michael Deininger, I studied chronic myeloid leukemia. My thesis evaluated mechanisms of kinase inhibitor resistance in patients treated with imatinib (Gleevec).
In oncology fellowship at University of California at San Francisco, I focused on the study of antibody-based therapeutics under the mentorship of Dr. Bin Liu. Antibody-drug conjugates (ADCs) are another rapidly growing approach to cancer treatment. With Dr. Liu, I conducting preclinical analyses of a novel ADC for multiple myeloma, with hope this this to soon lead to transition to the clinic.
Now a faculty member at UC Denver in the Hematology division, I oversee a translational research laboratory focused on novel therapy development and optimization for multiple myeloma and care for patients with myeloma and related plasma cell disorders from Colorado and adjoining areas.