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Robert H. Allen, M.D.

Professor of Medicine

Co-Head Division of Hematology

 CURRICULUM VITAE 

 

Medical School:  Washington University School of Medicine, St. Louis, Missouri

 

Postgraduate training:

1966-1967            Intern in Medicine, Parkland Memorial Hospital, Dallas, Texas

1967-1969            Staff Associate, National Institute of Arthritis, Metabolism and Digestive    Diseases, Bethesda, Maryland

1969-1970            Senior Resident in Medicine, Barnes Hospital, St. Louis, Missouri

1970-1972            Fellow in Hematology/Oncology, Washington University School of Medicine, St. Louis, Missouri

 

 

When arrived at UCD: 1977

 

Past and current professional positions:

1972-1975           Assistant Professor of Medicine, Washington University School of Medicine, St. Louis, Missouri

1975-1977          Associate Professor of Medicine, Washington University School of Medicine, St. Louis, Missouri

1977-Present        Professor of Medicine, University of Colorado School of Medicine, Denver, Colorado

1977-1998           Director, Division of Hematology, University of Colorado School of Medicine, Denver, Colorado

1992-Present       Cleo Meador and George Ryland Scott Professor of Hematology Research,

    University of Colorado School of Medicine, Denver, Colorado

1998-Present       Co-Director, Division of Hematology, University of Colorado School of Medicine, Denver, Colorado

 

 

Memberships and other information:        

American Society of Hematology

American Society of Biological Chemists    

American Society for Clinical Investigation

Association of American Physicians

           

Board Certification:

            Internal Medicine, 1974

            Hematology, 1976

 

Awards received:

     Alpha Omega Alpha

1974-1978            American Cancer Society Faculty Research Award

1986                     MERIT Award, National Institute of Diabetes and Digestive and Kidney

                             Diseases, NIH

1994                     Chairman, FASEB Summer Research Conference on Folic Acid, Vitamin B12                

                             and One Carbon Metabolism, Copper Mountain, Colorado

 

 

Major Scientific Interest:  Absorption, transport and metabolic role of cobalamin and cobalamin analogues.

 

Major Clinical Interest:  Diagnosis and clinical manifestations of cobalamin and folate deficiencies. 

 

 

Representative Publications:

  1. Allen, Robert H., and Majerus, Philip W.  Isolation of vitamin B12-binding proteins using affinity chromatography.  III.  Purification and properties of human plasma transcobalamin II.  J Biol Chem 247:7709-7717, 1972.
  2. Kolhouse, J. Fred, Kondo, Haruki, Allen, Nancy C., Podell, Elaine R. and Allen, Robert H.   Cobalamin analogues are present in human plasma and can mask cobalamin deficiency because current radioisotope dilution assays are not specific for true cobalamin.  New Engl J Med 299:785-792, 1978.
  3. Kondo, Haruki, Kolhouse, J. Fred and Allen, Robert H.   Presence of cobalamin analogues in animal tissues.  Proc. Natl. Acad. Sci. U. S. A. 77:817-821, 1980.
  4. Kovachy, Robin J., Copley, Shelley D. and Allen, Robert H.  Recognition, isolation, and characterization of rat liver D-methylmalonyl coenzyme A hydrolase.  J Biol Chem 258:11415-11421, 1983.
  5. Stabler, Sally P., Marcell, Paul D., Podell, Elaine R., Allen, Robert H., Savage, David and Lindenbaum, John.  Elevation of total homocysteine in the serum of patients with cobalamin or folate deficiency detected by capillary gas chromatography-mass spectrometry.  J Clin Invest 81:466-474, 1988.
  6. Lindenbaum, John, Healton, Edward B., Savage, David G, Brust, John C.M., Garrett, Thomas J., Podell, Elaine R., Marcell, Paul D., Stabler, Sally P. and Allen, Robert H.   Neuropsychiatric disorders caused by cobalamin deficiency in the absence of anemia or macrocytosis.  New Engl J Med 318:1720-1728, 1988.
  7. Allen, Robert H., Stabler, Sally P., Savage, David G. and Lindenbaum, John.  Metabolic abnormalities in cobalamin (vitamin B12) and folate deficiency.  FASEB J 7:1344-1353, 1993.
  8. Niyikiza, Clet, Baker, Sharyn, Seitz, David E., Walling, Jackie M., Nelson, Katrina, Rusthoven, James J., Stabler, Sally P., Paoletti, Paolo, Calvert, A. Hilary and Robert H. Allen. Homocysteine and methylmalonic acid: Markers to predict and avoid toxicity from pemetrexed therapy. Mol Cancer Ther 1:545-552, 2002.
  9. Allen RH, Stabler SP.  Identification and quantitation of cobalamin and cobalamin analogues in human feces.  Am J Clin Nutr 87:1324-1335, 2008.