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Hong Wang, Ph.D.

Assistant Professor of Medicine


Dr. Wang joined the Division of Endocrinology in 2006. She received her Bachelor of Science degree in chemistry from Nanjing University, Nanjing, China in 1990. She then came to United States to pursue graduate study and received her Ph.D. in Biochemistry from University of Utah, Salt Lake City, Utah in 1998. She went on to get postdoctoral training in Huntsman Cancer Institute at University of Utah, where she researched in the area of transcriptional regulation mechanism and cancer biology. Before coming to CU Denver, she was the Director of Protein Expression and Purification Facility at Colorado State University. Dr. Wang currently directs the basic science research group of Dr. Robert H. Eckel and works closely with Dr. Eckel on using genetically modified mouse models to study the mechanism of metabolic diseases such as obesity, dyslipidemias, diabetes mellitus, and other metabolic associated disorders such as cardiovascular diseases and dementia.

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  • Lipid Metabolism
  • Energy Balance
  • Dementia
  • Cardiac Dysfunction
  • Gender Differences

Selected Publications

  1. Regulation of mitochondrial biogenesis by lipoprotein lipase in muscle of insulin-resistant offspring of parents with type 2 diabetes.
    Morino K, Petersen KF, Sono S, Choi CS, Samuel VT, Lin A, Gallo A, Zhao H, Kashiwagi A, Goldberg IJ, Wang H, Eckel RH, Maegawa H, Shulman GI.
    Diabetes. 2012 Apr;61(4):877-87. Epub 2012 Feb 24.
  2. Deficiency of lipoprotein lipase in neurons modifies the regulation of energy balance and leads to obesity.
    Wang H, Astarita G, Taussig MD, Bharadwaj KG, DiPatrizio NV, Nave KA, Piomelli D, Goldberg IJ, Eckel RH.
    Cell Metab. 2011 Jan 5;13(1):105-13.
  3. Lipoprotein subfraction cholesterol distribution is proatherogenic in women with type 1 diabetes and insulin resistance.
    Maahs DM, Hokanson JE, Wang H, Kinney GL, Snell-Bergeon JK, East A, Bergman BC, Schauer IE, Rewers M, Eckel RH.
    Diabetes. 2010 Jul;59(7):1771-9. Epub 2010 Apr 14.
  4. Lipoprotein lipase: from gene to obesity.
    Wang H, Eckel RH.
    Am J Physiol Endocrinol Metab. 2009 Aug;297(2):E271-88. Epub 2009 Mar 24. Review.
  5. The metabolic syndrome.
    Cornier MA, Dabelea D, Hernandez TL, Lindstrom RC, Steig AJ, Stob NR, Van Pelt RE, Wang H, Eckel RH.
    Endocr Rev. 2008 Dec;29(7):777-822. Epub 2008 Oct 29. Review.
  6. Skeletal muscle-specific deletion of lipoprotein lipase enhances insulin signaling in skeletal muscle but causes insulin resistance in liver and other tissues.
    Wang H, Knaub LA, Jensen DR, Young Jung D, Hong EG, Ko HJ, Coates AM, Goldberg IJ, de la Houssaye BA, Janssen RC, McCurdy CE, Rahman SM, Soo Choi C, Shulman GI, Kim JK, Friedman JE, Eckel RH.
    Diabetes. 2009 Jan;58(1):116-24. Epub 2008 Oct 24. Erratum in: Diabetes. 2010 Mar;59(3):756.

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Graduate School
Ph.D., University of Utah (1998)

Undergraduate School
B.S., Nanjing University, Nanjing China (1990)

Fellowship
University of Utah (2001)


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