The Department of Medicine at the Anschutz Medical Campus boasts top medical care for patients, as well as fellowships and endowments. The Grand Rounds Schedule includes all events for divisions under the department.

HLA genetics in solid organ and stem cell transplantation

Umbilical cord blood banking

Clinical immunology

Clinical Team:

Michael Aubrey, MS               Katharine Spanjer                          Kelly Greenlee

Sarah Bruno                         Sabine Stockinger                          Jane Oppenheim, MPH

Linda Cagle                          Linda Tapia                                     Pat Supon, PhD

Cheri Anobile                        Stephanie Warnell                          Celeste Robledo

Shannon Flannery                Gina Wedermyer                             Ingrid Andersen

Tate Hermanson                   Cassandra Taylor                            Kristin Schultz

Randall Huser                       Christine Miller                                 Sarah Kuenne

Dianne McLaughlin                Sandra Fradenburg                         Nick Inhelder

Sharon Miller                         Amber Ortegon                               Kristen Blackburn

Lora Offord                           Tonya Serrano                                 Kit Mausbach

Diana Ponce                          Garrett Hedlund                              Adrianna Chavez

Zach Swensen                      Brendan Ryan                                                                                    

Effects of smoking on pulmonary immune responses; HLA epitopes and immune mediated diseases.

Research Team:

Min Zhang, MD

Hongbin Dong, PhD

Stringer KA, Freed BM, Dunn JS, Ayers S, Gustafson DL and Flores SC.  Particulate phase cigarette smoke increases MnSOD, NQO1 and Cinc-1 in rat lungs.  Free Rad Biol Med.  2004; 37:1527.

Dunn JS, Freed BM, Gustafson DL and Stringer KA.  Inhibition of human neutrophil reactive oxygen species production and p67phox translocation by cigarette smoke extract.  Atherosclerosis.  2005; 179:261.

Lambert C, McCue J, Portas M, Ouyang Y, Li J, Rosano TG, Lazis A and Freed BM. Acrolein in cigarette smoke inhibits T cell activation.  J Allergy Clin Immunology.  2005; 116:916.

Bill JR, Mack DG, Falta MT, Maier LA, Sullivan AK, Joslin FG, Martin AK, Freed BM, Kotzin BL and Fontenot AP.  Beryllium presentation to CD4+ T cells is dependent on a single amino acid residue of the MHC class II β chain.  J Immunology.  2005; 175:7029.

Meyer MA, Dwyer-Nield LD, Hurteau G, Keith RL, Ouyang Y, Freed BM, Kisley LR, Geraci MW, Bonventre JV, Nemenoff RA and Malkinson AM.  Attenuation of the inflammatory response following butylated hydroxytoluene (BHT) treatment of cytosolic phospholipase A2 (cPLA2) null mice.  Am J Physiol Lung Cell Mol Physiol.  2006; 290:2160.

Gibney EM, Cagle L, Freed B, Warnell SE, Chan L and Wiseman AC.  Detection of donor-specific antibodies using HLA-coated microspheres: another tool for kidney transplant risk stratification.  NephrologyDialysis and Transplantation.  2006; 21:2625.

Frazer-Abel A, McCue J, Lazis S, Portas M, Lambert C and Freed BM.  Cigarette tar phenols impede T cell cycle progression by inhibiting cyclin-dependent kinases.  Mol Immunol.  2007; 44:488.

Lambert C, Li J, Jonscher K, Quintana M, Harvey JA and Freed BM.  Acrolein inhibits cytokine gene expression by alkylating cysteine and arginine residues in the NF-kB1 DNA-binding domain.  J Biol Chem.  2007; 282:19666.

Mack CL, Falta ML, Sullivan AK, Karrer F, Sokol RJ, Freed BM and Fontenot AP.  Oligoclonal expansions of CD4+ and CD8+ T cells in the target organ of patients with biliary atresia.  Gastroenterology.  2007; 133:278.

Freed BM and Lambert C.  Redox regulation of transcription by cigarette smoke.  In Comprehensive Toxicology (in press).  2010.

Marketing a Killer: The Art of Cigarette Advertising. University of Colorado School of Medicine Arts in Medicine Lectures, 2004.

Recent Advances in Cord Blood Transplantation. Northside Hospital, Atlanta, GA 2005

Recent Developments in Cord Blood Transplantation. Annual Meeting of the Association of Medical

Laboratory Immunologists, Denver, 2005.

Cord Blood Banking-A US Perspective. Brazilian National Cancer Institute, Rio de Janeiro, Brazil, 2005.

Administration of Cord Blood Banks for a National Network. Annual Meeting of American Association of Blood Banks (AABB), Seattle, 2005.

HLA and Autoimmunity. The Children’s Hospital, Denver, CO, 2005.

Cord Blood Transplantation. Southern California Branch American Society Microbiology, 2006.

Regulation of Inflammatory Gene Expression by Cigarette Smoke Aldehydes.  Philip Morris International, Cologne, Germany, 2008.

Induction of Proinflammatory and Immunosuppressive Immune Responses by Cigarette Smoke Aldehydes. Society of Toxicology Annual Meeting, Baltimore, Maryland, 2009.

International Standards for Cord Blood Banking. Mediconex Annual Meeting, Cairo, Egypt, 2009.

The Business of Cord Blood Banking: Legal, Regulatory and Financial Barriers to Success.  Mediconex Annual Meeting, Cairo, Egypt, 2009.

Current Status of Cord Blood Transplantation.  Mediconex Annual Meeting, Cairo, Egypt, 2009.       

The Future of Stem Cell Therapy.  Mediconex Annual Meeting, Cairo, Egypt, 2009.

Smoking and Immunity.  University of Rochester School of Medicine 2010.