Taylor’s laboratory focuses on patients and families with inherited
cardiomyopathies, major causes of heart failure and heart transplantation.
Our work include DNA sequencing, cell-modeling, biomechanical studies, and
natural history studies. In addition to descriptive and mechanistic studies in
cardiomyopathies, the group is involved in clinical trials in rare forms of hereditary
cardiomyopathy where specific mutational sub-classes of disease are targeted
with therapies designed to benefit those individuals with mutations in key
subsets of cardiomyopathy genes.
cardiomyopathies, Dr. Taylor is involved in therapeutic studies in rare inborn
errors of metabolism including past and ongoing treatment trials in Gaucher,
Fabry, and Pompe diseases. The rapid advances from genetic discovery to
and understanding of pathophysiology to treatment development ensures that
additional studies in rare genetic conditions will shortly be arriving on the
Matthew R. G. Taylor MD, PhD
Director, Adult Clinical Genetics, Department of Medicine
303-724-1400 (office) 720-848-0469 (fax)