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Taylor Lab


Dr. Taylor’s laboratory focuses on patients and families with inherited cardiomyopathies, major causes of heart failure and heart transplantation.  Our work include DNA sequencing, cell-modeling, biomechanical studies, and natural history studies. In addition to descriptive and mechanistic studies in cardiomyopathies, the group is involved in clinical trials in rare forms of hereditary cardiomyopathy where specific mutational sub-classes of disease are targeted with therapies designed to benefit those individuals with mutations in key subsets of cardiomyopathy genes.
 
Beyond cardiomyopathies, Dr. Taylor is involved in therapeutic studies in rare inborn errors of metabolism including past and ongoing treatment trials in Gaucher, Fabry, and Pompe diseases.  The rapid advances from genetic discovery to and understanding of pathophysiology to treatment development ensures that additional studies in rare genetic conditions will shortly be arriving on the scene. 
         
Active disease registries include: The Familial Cardiomyopathy Registry, the Lysosomal Storage Disease Registry, the Danon Disease Registry and the Lamin A/C Disease Registry.
 
Matthew R. G. Taylor MD, PhD
Director, Adult Clinical Genetics, Department of Medicine
303-724-1400 (office)   720-848-0469 (fax) 720-848-0782(appointments)