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Welcome to the Integrated Department of Immunology at the University of Colorado - School of Medicine and National Jewish Health.

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Autoimmunity


 

 

Susan Boackle, MD - Role of complement receptor 2 in human and mouse systemic lupus erythematosus. Pathogenesis of systemic lupus erythematosus.

John Cambier, PhD - Mechanisms underlying loss of B cell anergy in T1D and SLE

Leonard Dragone, MD/PhD - SLAP deficiency in B and T cell development, repertoire selection and autoimmune thresholds.

Andrew Fontenot, MD - COPD and autoimmunity

Kathryn Haskins, PhD - Pathogenic and regulatory T cells in type 1 diabetes. Investigation of autoantigens for pathogenic T cells in type 1 diabetes.

Peter Henson, MD/PhD - Defective apoptotic cell clearance. Effects of TNFa in autoimmune responses

V. Michael Holers, MD - Evolution of autoimmunity in RA. Prediction and prevention.

Dirk Homann, MD/MA - Mechanisms of pathogenic and regulatory T cell function in type 1 diabetes/ therapeutic vaccination.

John Kappler, PhD - Identification of T cell epitopes in diabetes and rheumatoid arthritis.

Philippa Marrack, PhD and John Kappler, PhD - Role of infection and interferons in breaking tolerance.

Rebecca O'Brien, PhD -
Spontaneous keratitis (corneal inflammation) in two T cell-deficient mouse strains.

Roberta Pelanda, PhD - Mechanisms of development and activation of autoreactive B cells.

Yosef Refaeli, PhD - Mechanisms of breach of B and T cell tolerance by MYC. Polyclonal autoimmune lymphoproliferative disease as a preneoplastic state for the development of lymphoid malignancies.

Dave Riches, PhD -
Mechanism of development of autoimmune-associated interstitial lung diease

Christina Roark, PhD - The role of gamma/delta T cells in CIA.

Lawrence Wysocki, PhD - T cell help to autoreactive B cells in systemic autoimmune disease.  Breaches in B cell self-tolerance at the germinal center stage of activation.