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Welcome to the Integrated Department of Immunology at the University of Colorado - School of Medicine and National Jewish Health.

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Survival and Apoptosis



Peter Henson, MD/PhD - Apoptosis in granulocytes. Surface changes on apoptotic cells leading to recogntion, removal and suppression of inflammation and immunity. Mechanisms and consequences of apoptotic cell removal.

John Kappler, PhD - Structures and interactions among apoptotic effector molecules.

Philippa Marrack, PhD and John Kappler, PhD - Pathways governing T cell death.

Terry Potter, PhD - Signal transduction through CD8 leading to apoptosis of an early thymocyte population

Yosef Refaeli, PhD - Mechanism of survival downstream of cytokine receptors. Role of apoptotic related genes in the initiation and maintenance of lymphoid neoplasia. Role of apoptosis related genes in acquired drug resistance in lymphomas and leukemias.

Dave Riches, PhD - Mechanism of fibroblast and myofibroblast survival in pulmonary fibrosis. Regulation of apoptosis by death receptor ligation in myofibroblasts - role in the regulation of would repair.

Linda van Dyk, PhD - Apoptosis and survival in virus infection.