Alper, S, McBride, S,
Lackford, B, Freedman, JH, and Schwartz, DA. Specificity and Complexity of the C. elegans Innate Immune Respone. Mol.
Cell. Biol. 27: 5544-5553 (2007).
Y, McBride SJ, Boyd, WA, Alper, S,
and Freedman, JH. Toxicogenomic Analysis of Caenorhabditis
elegans Reveals Novel Genes and Pathways in the Resistance to Cadmium
Toxicity. Genome Biol. 8: R122 (2007).
Alper, S, Laws, R, Lackford,
B, Boyd, WA, Dunlap, P, Freedman JH, and Schwartz, DA. Identification of Novel
Innate Immunity Genes and Pathways Using a Comparative Genomics Approach. Proc.
Natl. Acad. Sci. USA. 105: 7016-7021. (2008).
IV, Wade, CM, Kang, HM, Alper, S,
Rutledge H, Lackford B, Eskin, E., Daly, MJ, and Schwartz DA. Identification of
novel genes that mediate innate immunity in inbred mice. Genetics. 183:
RM, Gally, F, Keeney, JG, Alper, S,
Gao, B, Han, M, Martin, RJ, Weinberger, AR, Case, SR, Minor, MN, Chu, HW.
Impact of cigarette smoke exposure on innate immunity: a Caenorhabditis elegans model. PLOS One. 4:e6860. (2009).
Alper, S, Mcelwee, M, Apfeld,
J, Lackford, B, Freedman, JH, and Schwartz, DA. The Caenorhabditis elegans germ line regulates distinct signaling
pathways to control lifespan and innate immunity. J. Biol. Chem. 285:
Alper, S. Model Systems to
the Rescue: the relationship between aging and innate immunity. Comm. and
Integr. Biol. 3(5): 409-414. (2010).
IV, Alper, S, Lackford, B, Rutledge,
H, Burch, LH, and Schwartz, DA. Novel Regulators of the Systemic Response to
Lipopolysaccharide (LPS). American J. Resp. Cell. Mol. Biol. 45:
IV, Jiang, W, Rutledge, HR, Lackford, B, Warg, LA, De Arras, L, Alper, S, Schwartz, DA, and Pisetsky,
DS. Identification of Novel Innate Immune Genes by Transcriptional Profiling of
Macrophages Stimulated with TLR Ligands. Molec Immunol. 48: 1886-95
10. De Arras, L, Yang,
IV, Lackford, B, Riches, DWH, Prekeris, R, Freedman, JH, Schwartz, DA, and Alper, S. Spatiotemporal inhibition of
innate immunity signaling by the Tbc1d23 RAB-GAP. J. Immunol. 188:
11. Victorino, F, and Alper, S. Identifying novel
spatiotemporal regulators of innate immunity. Immunologic Research. 55:
12. De Arras, L, Seng, A,
Lackford, B, Keikhaee, MR, Bowerman, B, Freedman, JH, Schwartz, DA, Alper, S. An evolutionarily conserved
innate immunity protein interaction network. J. Biol. Chem. 288:
Arras, L and Alper, S. Limiting of
the innate immune response by SF3A-dependent control of MyD88 alternative mRNA
splicing. PLOS Genetics 9(10):e1003855 (2013).
Arras, L, Laws, R, Leach, S, Pontis, K, Freedman, JH, Schwartz, DA and Alper, S. Comparative genomics RNAi
screen identifies Eftud2 as a novel regulator of innate immunity. Genetics
published online Dec 20 (2013).
Arras, L and Alper, S. Using
RNAi-interference to investigate the innate immune response in mouse
macrophages. J. Vis. Exp. in press (2013).
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