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Welcome to the Integrated Department of Immunology at the University of Colorado - School of Medicine and National Jewish Health.

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Nichole Reisdorph PhD

Assistant Professor of Immunology

Dr. Nichole Reisdorph is an Assistant Professor in Immunology at National Jewish Health and was previously Director of the proteomics and mass spectrometry based-metabolomics divisions within Clinical Nutrition Research Unit (CNRU) mass spectrometry facility at the University of Colorado Denver. It is her primary responsibility to create a proteomics and metabolomics facility to accommodate the needs of National Jewish and regional investigators, quite literally from the ground up. She was trained in mass spectrometry, proteomics, and mass spectrometry-based metabolomics at the Mass Spectrometry Core of the Scripps Research Institute, La Jolla, CA (Director: Dr. G. Siuzdak).

Dr. Reisdorph's research is designed to integrate clinical proteomics, metabolomics, and bioinformatics in order to develop and customize clinically relevant methodologies to diagnose or monitor disease states. Results from these studies will also significantly enhance the knowledge of the biochemical mechanisms of diseases. In addition, Dr’s Reisdorph’s facility will specialize in post-translational modification analysis as well as the identification of differentially regulated proteins from a variety of sources including cell extracts, biofluids, and tissue samples. Dr. Reisdorph uses a variety of techniques in her work, including two-dimensional gel electrophoresis, DiGE, tandem mass spectrometry, and quantitative labeling and non-labeling strategies.

Dr. Reisdorph organizes proteomics hands-on workshops and web-based courses through National Jewish and the University of Colorado Denver. Since 2005, Dr. Reisdorph and her team have instructed almost a dozen 3-4 day workshops, for a total of over 120 individuals, who come from a variety of backgrounds. Dr. Reisdorph is currently expanding her training program to include additional hands on courses, such as quantitative proteomics, and distance-learning courses, such as database searching.

  • Bowler, R., Ellison, M., Reisdorph, N. (2006) Translating Basic Research into Clinical Practice: Proteomics in Pulmonary Medicine (Invited Review). CHEST (Accepted)
  • Christians, U., Reisdorph, N., Klawitter, J., Schmitz,V. (2005) Biomarkers of immunosuppressant toxicity (Review). Current Opinion in Organ Transplantation, 10:284-294.
  • Reisdorph, N.A. & Small, G.D. (2004) The CPH1 gene of Chlamydomonas encodes two forms of cryptochrome whose levels are controlled by light-induced proteolysis. Plant Physiology, 134:1546-1554
  • Kriwacki, R., Reisdorph, N., Siuzdak, G. (2004) Protein structure characterization with mass spectrometry. Spectroscopy, 18:37-47.
  • Reisdorph N., Thomas J.J., Katpally U., Chase E., Harris K., Siuzdak G., Smith T.J. (2003) Human rhinovirus capsid dynamics is controlled by canyon flexibility. Virology, 314:34-44.
  • Koster, K.L., Reisdorph, N., Ramsay, J.L. (2003) Changing desiccation tolerance of pea embryo protoplasts during germination. J Exp Bot. 54:1607-14.
  • Meyers A., Trauger S., Webb W., Reisdorph N., Wranik C., Peters E., Siuzdak G. (2003) Protein profiling with mass spectrometry. Spectroscopy 17:1-15
  • Reisdorph, N.A. & Koster, K.L. (1999) Progressive loss of desiccation tolerance in germinating pea (Pisum sativum) seeds. Physiologia Plantarum 105: 266-271.

View of Recent Publications in PubMed