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Glomerular filtration rate calculation

Glomerular Filtration Rate calculation spreadsheet (including biexponential curve fitting in Excel)


FOR RESEARCH PURPOSES ONLY
The DenverGFR V1.02e spreadsheet can be downloaded here: link
(sheet with metric units can be downloaded here (V1.02eu): metric_version_link )
Worksheet instructions and an example can be downloaded here: link
 
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This program is designed to calculate GFR measurements from blood samples taken from patient after administration of a low dose (~20 uCi) of I-125.
 
In this sheet, full curve characterization of plasma activity curves is calculated using biexponential modelling. In addition, GFR calculations are derived using single compartment methods and single time point methods, for comparison.
 
Our GFR worksheet is modelled after the protocols and calculations described in:
Assessment of glomerular filtration rate measurement with plasma sampling: a technical review, Murray AW, Barnfield MC, Waller ML, Telford T, Peters AM, JNMT, 2013 (link)
 
Version 1.0 - [Feb 2014] : initial release
Version 1.01 - [Sept 2014] : added capicity to handle non-conforming data point (not likely, but possible to occur)
Version 1.02 - [Feb 2014] : added selection of isotope for user (I-129, Tc-99m, Cr-51)
 
Please address any questions, or requests for an editable worksheet, to Adam Kesner: adam.kesner@ucdenver.edu. We would love to hear if you found this resource useful!