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You have reached the Web site for the Department of Pathology at the University of Colorado Denver.

Colorado Genetics Labs
 

Solid Tumor or Lymph Node Chromosome Analysis


 

Indication

 

Chromosome analysis of solid tumor or lymph node biopsies are performed to detect acquired chromosome abnormalities associated with specific tumors or lymphoma.

 

Methodology

15-20 metaphases are examined and a minimum of 3 karyotypes are prepared. Molecular cytogenetic studies using fluorescence in situ hybridization (FISH) are often performed in addition to solid tumor or lymph node chromosome analysis. See FISH for Chromosome Abnormalities in Cancer 

 

Specimen Requirements

    • Submit 0.2-1.0 cm3 or as large a sample as possible
    • Collect aseptically, avoiding areas of necrosis
    • Place in sterile, plastic screw top tube filled with sterile transport media
    • Label specimen tube with patient’s name and a second identifer (ex: DOB or hospital ID number)
    • Maintain specimen at room temperature and transport to the Colorado Genetics Laboratory immediately
       

Samples must be accompanied by a completed Test Request Form.  Indicate test request in the “Cancer Specimens” section of the form, and include clinical data and diagnostic issues, which help focus culture set up and analysis.