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Lian Zhang, MD, PhD

Assistant Professor


  • MD, Hebei United Medical University
  • PhD, University of Colorado Health Science Center

Postdoctoral Education:​ 

  • Anatomic and Clinical Pathology Residency, University of Colorado Denver, School of Medicine (2012-2016)
  • Surgical Pathology/Genitourinary and Renal Pathology Fellowship, University of Colorado Hospital (2016-2017)


  • Surgical Pathology
  • Renal Pathology
  • Autopsy

Selected Publications:

Peer Reviewed Research Articles (Published)

  • Perales R, Erickson B, Zhang L, Kim H, Veliquett E, Bentley D. Gene promoters dictate histone occupancy within genes. EMBO J. 2013 Oct 2; 32(19):2645-5
  • Perales R, Zhang L, and Bentley DL. Histone occupancy in vivo at the '601' nucleosome positioning sequence is determined by transcriptional history. Molecular and Cellular Biology, 2011 Aug; 31(16): 3485-96
  • Goehe RW, Shultz JC, Murudkar C, Usanovic S, Lamour NF, Massey DH, Zhang L, Camidge DR, Shay JW, Minna JD, Chalfant CE. HnRNP L regulates the humorigenic capacity of lung cancer xenografts in mice via caspase-9 pre-mRNA processing. Journal of Clinical Investigation, 2010 Nov 1; 120(11): 3923-39
  • Zhang L, Kavanagh BD, Thorburn AM, Camidge DR. Preclinical and clinical estimates of a cancer’s basal apoptotic rate predict for the amount of apoptosis induced by subsequent pro-apoptotic stimuli. Clinical Cancer Research, 2010 Sep 1; 16(17):4478-89
  • Seward DJ, Cubberley G, Kim S, Schonewald M, Zhang L, Tripet B, Bentley DL. Demethylation of trimethylated histone H3 Lys4 in vivo by JARID1 JmjC proteins. Nature Structural & Molecular Biology. 2007 Feb; 14(3): 240-242
  • Zhang L, Schroeder S, Fong N, Bentley DL. Altered nucleosome occupancy and histone H3K4 methylation in response to increased transcriptional stress. The EMBO Journal. 2005 Jul; 24(13): 2379-2390 
  • Zhang L, Jia G, Li WM, Guo RF, Cui JT, Yang L, Lu YY. Alteration of the ATM gene occurs in gastric cancer cell lines and primary tumors associated with cellular response to DNA damage. Mutation Research. 2004 Jan; 557(1): 41-51