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Bradford J. Siegele, MD

Assistant Professor, Hematopathology and Pediatric Pathology


Education:
  • AB, Duke University, Durham, NC (1999)
  • JD, Harvard Law School, Cambridge, MA (2005)
  • Pre-Med, Columbia University, New York, NY (2006)
  • MD,  University of Texas Southwestern Medical Center at Dallas, Dallas, TX (2012)
  • Anatomic & Clinical Pathology Residency, University of Colorado, Aurora, CO (2016)
  • Pediatric Pathology Fellowship, Boston Children's Hospital, Boston, MA (2017)
  • Hematopathology Fellowship, Massachusetts General Hospital, Boston, MA (2018)

Specialty and Subspecialty Certification:
  • Anatomic & Clinical Pathology (July, 2016)
  • Pediatric Pathology (September, 2017)

Professional Organizations:
  • American Society of Clinical Pathology (ASCP) (2017-present)
  • Massachusetts Medical Society (2016-present)
  • Society for Pediatric Pathology (SPP) (2014-present)
  • College of American Pathologists (CAP) (2012-present)

Professional Activities:
  • Moderator, Neoplasia Platform Presentation Session, Society for Pediatric Pathology, Spring Meeting (2018)
  • Chief Hematopathology Fellow, Department of Pathology, Massachusetts General Hospital (2017-2018)
  • Chief Fellow, Department of Pathology, Boston Children’s Hospital​ (2016)
  • Resident Leader, Global Health Initiative, Department of Pathology, University of Colorado Anschutz Medical Campus (2014-2016)
  • Resident Instructor, Life Cycle and Disease/Defense and Life Cycles courses, University of Colorado Anschutz Medical School (2012-2016)
  • Instructor, Multi-institute seminar series on comparative mouse and human oral anatomy and histology, National Institutes of Health (2011)
  • Course Director and Instructor, Physiology, Metabolic Disorders, and Cardiovascular Physiology, University of Texas Southwestern Medical School (2008)

Honors and Awards:
  • Lotte Strauss Prize for Meritorious Work by an Individual 40 years of Age or Younger (Finalist), Society for Pediatric Pathology, Spring Meeting (2017)
  • Robert H. Fennell, Jr., M.D. Award for Excellence in Education, University of Colorado Anschutz Medical Campus, Department of Pathology (2016)
  • Resident in Service Examination (RISE) Award, Highest RISE Score in 1st (tied), 2nd, 3rd (tied), 4th years, University of Colorado Anschutz Medical Campus, Department of Pathology (2013-2016)
  • Medical Student Teaching Award, University of Colorado Anschutz Medical Campus, Department of Pathology (2014)
  • University of Colorado Clinical Laboratories Dashboard Award for Special Assistance in the Stragetic Initiative for Quality Assurance and Improvement (2012)
  • Alona Evans Prize for Best Original Manuscript in International Law, Duke University (1999)

Publications:
Iyasere, CA, Takvorian, RW, Simeone, FJ, Siegele, B. “A 39-year-old man with epistaxis, pain and erythema of the forearm, and pancytopenia.” N Engl J Med. (epub ahead of print).

Martin, D, Degese, MS, Vitale-Cross, L, Iglesias-Bartolome, R, Valera, JLC, Wang, Z, Feng, X, Yeerna, H, Vadmal, V, Moroishi, T, Thorne, RF, Zaida, M, Siegele, B, Cheong, SC, Molinolo, AA, Samuels, Y, Tamayo, P, Guan, KL, Lippman, SM, Lyons, JG, Gutkind, JS. “Assembly and activation of the Hippo signalome by FAT1 tumor suppressor.”  Nat Commun. 2018 July 9. Doi: 10.1038/s41467-018-04590-1 (epub ahead of print).

Siegele, B, Nardi, V. “Laboratory testing in BCR-ABL1-like (Philadelphia-like) B-lymphoblastic leukemia/lymphoma. Am J Hematol. 2018 Apr 26. Doi: 10.1002/ajh.25126 (epub ahead of print).

Rosenblatt, S, Wolter, N, Siegele, B, Brodsky, J. “Primary parotid lymphoma presenting as a recurrent cystic mass: A case report.” Laryngoscope. 128(4):998-1001, 2018.

Wolter, N, Siegele, B, Cunningham, M. “Cystic cervical teratoma: A diagnostic and management challenge.” Int’l J Ped Otorhinolaryngol 95:97-100, 2017.

Siegele, B, Roberts, J, Black, J, Rudzinski, E, Vargas, S, Galambos, C, “DUX4 immunohistochemistry is a highly ensitive and specific marker for CIC-DUX4 fusion positive round cell tumor” Am J Surg Pathol. 41:423-29, 2017.

Siegele, B, Liang, X. Hematopathology, in Dishop, MK, ed. Atlas of Pediatric Pathology, Springer, New York, NY   (In press).

Siegele, B. Head & Neck, in Dishop, MK, ed. Atlas of Pediatric Pathology, Springer, New York, NY (In press).

Siegele, B. Adrenal Gland, in Dishop, MK, ed. Atlas of Pediatric Pathology, Springer, New York, NY (In press).

Siegele, B, Iczkowski, K, La Rosa, F. “Carcinosarcoma of the prostate in a patient with previous prostatic adenocarcinoma, status post brachytherapy: A case report and review of the literature,” Intl J Clin Exper Pathol. 9(7):7724-32, 2016.

Siegele, B, Shilo, K, Chao, BH, Carbone, D, Zhao, W, Ioffe, O, Franklin, W, Edelman, MJ, Aisner, DL. “Epidermal growth factor receptor (EGFR) mutations in small cell lung cancers: Two cases and a review of the literature,” Lung Cancer. 95:65-72, 2016.

Patel, V, Iglesias-Bartolome, R, Siegele, B, Marsh, C, Leelahavanichkul, K, Molinolo, A, Gutkind, JS.  “Cellular Systems for Studying Human Oral Squamous Cell Carcinomas,” in Advances in Experimental Medicine and Biology: Human Cell Transformation. 720(1):27-38, 2012.

Siegele B, Cefalu C, Holm N, Sun G, Tubbs J, Meschonat C, Odaka Y, DeBenedetti A, Ghali GE, Chu Q, Mathis JM, Li BD. “eIF4E-targeted suicide gene therapy in a minimal residual mouse model for metastatic soft-tissue head and neck squamous cell carcinoma improves disease-free survival,” J Surg Res. 148:83-9, 2008.