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Regie Santos-Cortez, MD, PhD

Associate Professor


Academic Office:
12700 E. 19th Avenue
Mail Stop #8606
Aurora, CO 80045

Phone: 303-724-0289
Lab: 303-724-0952
Fax: 303-724-4553


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Dr. Regie Santos-Cortez is an Associate Professor performing basic research in the Department of Otolaryngology. Her R01-funded project aims to identify novel genes and variants that are involved in susceptibility to otitis media and changes in the middle ear microbiome. This project has a collection of DNA samples and sequence data including exomes from >1,000 families and patients from the US, Philippines and Finland, as well as middle ear tissues and swabs and data from multiple head and neck sites for microbiome studies. Recently the lab has collected DNA, RNA and microbial samples from collaborating otologists and pediatric otolaryngologists within the Department and submitted samples for sequencing and analyses. These multi-omic studies allow for data integration that leads to a deeper understanding of otitis media pathophysiology, and hopefully in the future this knowledge may lead to improved management of otitis media. The collaborative network supporting this project involves investigators from multiple US and international institutions who not only provide clinical data and samples for study but also contribute clinical, genetic and statistical expertise to the project.​


Lab Team


  • Baylor College of Medicine – Suzanne Leal
  • Infectious Diseases Division, Department of Medicine, University of Colorado – Daniel Frank
  • University of California San Diego – Allen Ryan
  • University of Helsinki – Lena Hafren
  • University of Maryland – Zubair Ahmed
  • University of Minnesota – Kathleen Daly
  • University of North Carolina – Karen Mohlke
  • University of San Carlos – Nanette Lee
  • University of Texas Medical Branch – Tasnee Chonmaitree
  • University of the Philippines Manila – Charlotte Chiong
  • University of Virginia – Michele Sale/Ani Manichaikul
  • University of Washington – Debbie Nickerson/Michael Bamshad​

  • Philippine Society of Otolaryngology – Head and Neck Surgery (Diplomate)
  • Association for Research in Otolaryngology
  • American Society of Human Genetics
  • International Society for Otitis Media
  • Elected Member, (CORLAS) ​Collegium Oto-Rhino-Laryngologicum Amicitiae Sacrum 

  • Tori Bootpetch Roberts, Professional Research Assistant, Dec. 2016-present 
  • Erin Baschal, Instructor, Nov. 2018-present​
  • Matthew Steritz, PRA, Dec. 2016-July 2018, currently at Burrell College of Osteopathic Medicine
  • Susannah Roberts, Summer Intern, 2017
  • Jonathan Xu, Summer Intern, 2017
  • Brett Wiesen, Summer Medical Student, 2018