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Marie Jetté, PhD, CCC-SLP

Assistant Professor


Clinical Office:
1635 N. Aurora Court, 6th Floor
Aurora, CO 80045
Appointments: 720-848-7900

Academic Office:
12700 E. 19th Avenue
Mail Stop #8606
Aurora, CO 80045
Phone: 303-724-1950​ 
Fax: 303-724-1961

Hospital Affiliation:

University of Colorado Hospital ​

Voice and Upper Airway Disorders Lab 

Summary of the Lab’s Work​

The larynx is a special organ that functions as both a valve to protect the airway and as a biomechanical vibrator to produce voice. Prolonged irritation of the laryngeal mucosa leads to inflammation and difficulties with vital laryngeal functions including voice, swallow, and respiration. My broad research interest is identifying the pathophysiology of laryngeal inflammation in patients with voice disorders, upper airway dyspnea, and chronic cough. 


Structure and Function of Chemical Receptors in the Laryngeal Epithelium​ 

One area of research focus is characterizing chemical receptors in the laryngeal epithelium including solitary chemosensory cells, taste buds, and polymodal nociceptive nerve fibers. We are specifically interested in how stimulation of chemical receptors may result in local inflammation via a neurogenic pathway. This research is a collaboration with Dr. Thomas Finger in Cell and Developmental Biology, Dr. Sue Kinnamon in Otolaryngology, and Drs. Matthew Clary and Jeremy Prager, otolaryngologists in our department.










​​
Our clinical research in Laryngology spans a broad range of topics related to patient outcomes and evaluation of new diagnostic technologies. 

Clinical research collaborators include Drs. Matthew Clary and Daniel Fink of Otolaryngology and Dr. Rena Yadlapati of Gastroenterology and Hepatology.​

Refereed Journal Articles

  • Jetté, M.E., Clary M.S., Prager, J.D., & Finger, T.E. (Under Review). Chemical Receptors of the Larynx: A Comparison of Human and Mouse. Laryngoscope.
  • Schneider, S., Clary, M., Fink, D. Wang, S.X., Chowdhury, F., Yadlapati, R., Jetté, M., & Courey, M. (In Publication). Voice Therapy Associated with a Decrease in Reflux Symptoms Index in Patients with Voice Complaints. Laryngoscope.
  • Jetté, M.E., Anderson, C.B., & Ramakrishnan, V.R. (2017). Case Report: Diagnosis of hypogeusia after oral exposure to commercial cleaning agent and considerations for clinical taste testing. F1000Research, 6, 373.
  • Hanshew, A.S., Jetté, M.E., Tadayon, S., & Thibeault, S.L. (2017). Assessment of swab and biopsy sampling methods for vocal fold microbiota studies. PLoS One, 12(3).
  • Hanshew, A.S., Jetté, M.E., Rosen, S.P., & Thibeault, S.L. (2017). Integrating the microbiota of the respiratory tract with the unified airway model. Respiratory Medicine, 126, 68-74.
  • Thomas, C., Jetté, M.E., & Clary, M.S. (2017). Factors associated with infectious laryngitis: A retrospective review of 15 cases. Annals of Otology, Rhinology & Laryngology, 126(5), 388-395.
  • Jetté, M.E., Seroogy, C.M., & Thibeault, S.L. (2017). Laryngeal T regulatory cells in the setting of smoking and reflux. The Laryngoscope, 127(4), 882-887.
  • Jetté, M.E., Dill-McFarland, K.A., Hanshew, A.S., Suen, G., & Thibeault, S.L. (2016). The human laryngeal microbiome: Effects of cigarette smoke and reflux. Scientific Reports, 6, 35882.
  • Stevens, K.A., Thomson, S.L., Jette, M.E., & Thibeault, S.L. (2016). Quantification of porcine vocal fold geometry. Journal of Voice, 30(4). 416-426.
  • Jetté, M.E. (2016). Toward an understanding of the pathophysiology of laryngeal inflammation. Perspectives of the ASHA Special Interest Groups: SIG3, 1, 7-13.
  • Branco, A., Bartley, S., King, S., Jetté, M., & Thibeault, S. (2015). Vocal fold myofibroblast profile of scarring. The Laryngoscope, 125(3), 110-117.
  • Hanshew, A.S., Jetté, M.E., & Thibeault, S.L. (2014). Characterization and comparison of bacterial communities in benign vocal fold lesions. Microbiome, 2(43).
  • Jetté, M.E., Gaumnitz, E.A., Birchall, M.A., Welham, N.V., & Thibeault, S.L. (2014). Correlation between reflux and multichannel intraluminal impedance pH monitoring in untreated volunteers. The Laryngoscope, 124(10), 2345-2351.
  • Jetté, M.E., Hayer, S.D., & Thibeault, S.L. (2013). Characterization of human vocal fold fibroblasts derived from chronic scar. The Laryngoscope, 123(3), 738-745.
  • King, S.N., Chen, F., Jetté, M.E., & Thibeault, S.L. (2013). Vocal fold fibroblasts immunoregulate activated macrophage phenotype. Cytokine, 61(1), 228-236.
  • Bartlett, R., Jetté, M.E., King, S.N., Schaser, A., & Thibeault, S.L. (2012). Fundamental approaches in molecular biology for communication sciences and disorders. Journal of Speech, Language, and Hearing Research, 55, 1220-1231.
  • Stepp, C.E., Heaton, J.T., Stadelman-Cohen, T.K., Braden, M.N., Jetté, M.E., & Hillman, R.E. (2011). Characteristics of phonatory function in singers and nonsingers with vocal fold nodules. Journal of Voice, 25(6), 714-724.
  • Stepp, C. E., Heaton, J. T., Braden, M. N., Jetté, M. E., Stadelman-Cohen, T. K., & Hillman, R. E. (2011). Comparison of neck tension palpation rating systems with surface electromyographic and acoustic measures in vocal hyperfunction. Journal of Voice, 25(1), 67-75.
  • Stepp, C. E., Heaton, J. T., Jetté, M. E., Burns, J.A., & Hillman, R. E. (2010). Neck surface electromyography as a measure of vocal hyperfunction before and after injection laryngoscopy. Annals of Otology, Rhinology, & Laryngology, 119(9), 594-601.
  • Awan, S.N., Roy, N., Jetté, M.E., Meltzner, G.S., & Hillman, R.E. (2010). Quantifying dysphonia severity using a spectral/cepstral-based acoustic index: Comparisons with auditory-perceptual judgments from the CAPE-V. Clinical Linguistics and Phonetics, 24(9), 742-758.

 

Book Chapters

  • Jetté, M.E. & Thibeault, S.L. (2014). Vocal fold extracellular matrix and wound healing. In J.S. Rubin, R.T. Sataloff, R.T., & G.S. Korovin (Eds.), Diagnosis and Treatment of Voice Disorders (4th ed.).
  • Jetté, M.E. & Thibeault, S. (2011). Morphology of vocal fold mucosa: Histology to genomics. In R.H. Colton, J.K. Casper, & R. Leonard (Eds.), Understanding Voice Problems: A Physiological Perspective for Diagnosis and Treatment (4th ed., pp 63-74).


Conference Proceedings

  • Stevens, K.A., Jetté, M.E., Thibeault, S.L., & Thomson, S.L. (2013). Quantification of porcine vocal fold geometry in three dimensions. Journal of the Acoustical Society of America, 133(5), 3617.

 

Scientific Abstracts

  • Conklin, M., Clary, M.S., Cuadrado, E.M., & Jetté, M.E. (2019, January). Effect of Unilateral Cordotomy on Perception of Dysphagia. Paper presented at the Combined Sections of the Triological Society, Coronado, CA.
  • Jetté, M.E. & King, S.N. (2018, November). Sense & Sensibility: Pain & Hypersensitivity in Laryngeal Disorders. Paper presented at the annual meeting of the American Speech-Language Hearing Association, Boston, MA.
  • Jetté, M.E., Clary M.S., Prager, J.D., & Finger, T.E. (2018, April). Chemical Receptors of the Larynx: A Comparison of Human and Mouse. Paper presented at the annual meeting of the Combined Otolaryngological Spring Meetings, American Laryngological Association, National Harbor, MD.
  • Jetté, M.E., Kinnamon, S.C., & Finger, T.E. (2017, April). Man vs. mouse: Comparative histology of chemosensory elements in the larynx. Poster presented at the annual meeting of the Association for Chemoreception Sciences, Bonita Springs, FL.
  • Jetté, M.E., Clary M.S., Fink, D.S., Litts, J.K., & Cuadrado, E.M. (2018, October). Grand Rounds: The Aging Larynx. Paper presented at the annual meeting of the Colorado Speech Language Hearing Association, Greenwood Village, CO.
  • Thomas, C., Jetté, M.E., & Clary, M.S. (2016, May). Microbes associated with chronic laryngitis: A preliminary study. Paper presented at the Combined Otolaryngological Spring Meetings, American Broncho-Esophagological Association, Chicago, IL.
  • Jetté, M.E., Seroogy, C.M., & Thibeault, S.L. (2016, May). Laryngeal T regulatory cells in the setting of smoking and reflux. Poster presented at the Combined Otolaryngological Spring Meetings, American Laryngological Association, Chicago, IL.
  • Jetté, M.E., Clary M.S., Prager, J.D., Kinnamon, S.C., & Finger, T.E. (2016, April). Taste buds and solitary chemosensory cells in the infant human larynx. Poster presented at the annual meeting of the Association for Chemoreception Sciences, Bonita Springs, FL.
  • Jetté, M.E. & Thibeault, S.L. (2015, November). Laryngeal microbes: Frenemies of the voice. Paper presented at the annual conference of the American Speech-Language Hearing Association, Denver, CO. Student Research Travel Award for best student abstract.
  • Branco, A., Bartley, S.M., King, S.N., Jetté, M.E., & Thibeault, S.L. (2015, May). Fibroblast-myofibroblast response in normal vocal folds: An in vitro model. Poster presented at the Combined Otolaryngological Spring Meetings, American Laryngological Association, Boston, MA. Third Place Poster Award.
  • Jetté, M.E., Gaumnitz, E.A., Birchall, M.A., Welham, N.V., Thibeault, S.L. (2014, May). Endoscopic laryngopharyngeal reflux findings are poorly correlated with combined multichannel intraluminal impedance pH monitoring. Paper presented at the Combined Otolaryngological Spring Meetings, American Laryngological Association, Las Vegas, NV.
  • Stevens, K.A., Jetté, M.E., Thibeault, S.L., & Thomson, S.L. (2013, June). Quantification of porcine vocal fold geometry in three dimensions. Paper presented at the 21st International Congress on Acoustics, Montreal, Canada.
  • Jetté, M.E., Hayer, S.D., & Thibeault, S.L. (2012, February). Characterization of vocal fold fibroblasts derived from human scar. Poster session presented at the annual conference of the Wisconsin Speech-Language Hearing Association, Milwaukee, WI.
  • Jetté, M., King, S., Bartlett, R., & Moore, J. (2012, November). Vocal folds of the future: Update on bench-to-bedside voice research. Paper presented at the annual conference of the American Speech-Language Hearing Association, Atlanta, GA. Student Research Travel Award for best student abstract.
  • Jetté, M., Bartlett, R., King, S., Schaser, A., & Thibeault, S. (2011, November). DNA, RNA, and protein: A basic science tutorial for SLPs. Paper presented at the annual conference of the American Speech-Language Hearing Association, San Diego, CA.
  • Awan, S., Roy, N., Jetté, M., Meltzner, G., & Hillman, R. (2010, November). Spectral/cepstral estimates of dysphonia severity from the CAPE-V. Paper presented at the annual conference of the American Speech-Language Hearing Association, Philadelphia, PA.
  • Jetté, M., Stadelman-Cohen, T., Braden, M., Cheyne, H., Heaton, J., & Hillman, R. (2008, November). Treating voice disorders with portable biofeedback. Poster session presented at the annual conference of the American Speech-Language Hearing Association, Chicago, IL.
  • Stepp, C., Heaton, J., Stadelman-Cohen, T., Braden, M., Jetté, M., & Hillman, R. (2008, November). Vocal fold kinematics in individuals with vocal hyperfunction. Poster session presented at the annual conference of the Society of Neuroscience, Washington, D.C.​

  • Jetté, M. (2018, July). The Chronicles of Cough: Behavioral + Medical Management. Invited workshop presented at the 15th Biennial Phonosurgery Symposium, Madison, WI. 
  • Jetté, M. (2018, July). Effects of Smoking and Reflux on the Laryngeal Microbiome. Invited talk prsented at the Upper Airway Microbiome in conjunction with the 15th Biennial Phonosurgery Symposium, Madison, WI.
  • Jetté, M. (2018, July). Behavioral Therapy for the Neurological Patient. Invited talk presented at the 15th Biennial Phonosurgery Symposium, Madison, WI. 
  • Jetté, M. (2018, April). Bugs and Barriers: Laryngeal Defenses in Chronic Laryngitis. Invited talk presented at the Southwest Laryngology Conference, Phoenix, AZ.  
  • Jetté, M. (2018, February). Chemical receptors of the larynx in mouse and human.  Invited talk presented at the Ultimate Mid-Winter Colorado Ski Meeting, Vail, CO.  
  • Jetté, M. (2016, September). Laryngopharyngeal Reflux: Fact and Fiction. Invited talk presented at the annual conference of the Colorado Speech-Language-Hearing Association, Greenwood Village, CO.
  • Jetté, M. (2013, April). Paradoxical Vocal Fold Motion: Demystifying a Confusing Condition. Invited talk presented at the annual conference of the Maryland Speech-Language-Hearing Association, Timonium, MD.​
  • ​​​Loan Repayment Program, Clinical Research, National Institutes of Health​​ (2016-2018)

  • Forty for 40 Outstanding Alumni, MGH Institute orf Health Professions (2017)

  • Best T32 Presentation Award, Resident Research Day​, University of Colorado, Department of Otolaryngology​ (2017)

  • Third Place Poster Award, American Laryngological Association​ (2016)

  • Polak Postdoctoral Travel Award​, Association for Chemoreception Sciences (2016)

  • Student Research Travel Award (Best Student Abstract), American Speech-Language Hearing Association​ (2015)​

  • Lessons for Success Research Workshop (Travel Award), American Speech-Language Hearing Foundation​ (2014)

  • Ray Kent Award, University of Wisconsin-Madison (2014)

  • Vilas Conference Grant, Graduate Student Collaborative - University of Wisconsin-Madison (2014)

  • Emma Allen Scholarship, University of Wisconsin-Madison (2013)

  • Vilas Conference Grant, Graduate Student Collaborative - University of Wisconsin-Madison (2012)

  • New Century Scholars Doctoral Scholarship, American Speech-Language Hearing Foundation (2012)

  • Student Research Travel Award (Best Student Abstract), American Speech-Language Hearing Association (2012)

  • Stanley Ewanowski Scholastic Award, Wisconsin Speech-Language Hearing Association Foundation (2011)


  • ​​American Speech-Language Hearing Association
  • Association for Chemoreception Sciences​