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RESEARCH & CLINICAL TRIALS

Saving sight through advanced treatment approaches.


 

 

Glaucoma:

     Trabeculectomy Study 
     Occlusion Prevention for Trabeculectomy Procedures Using Combination Ranibizumab and Mitomycin
     C (MMC) During Surgery (OCTOPUS STUDY) - Malik Y Kahook, MD.

     Laser Study
     A Randomized Prospective, Physician-Masked, Controlled Trial Comparing Ketorolac Tromethamine
     0.4% and Prednisolone Acetate 1% in Reducing Post- Selective Laser Trabeculoplasty Anterior Chamber
     Flare and Cells - Malik Y Kahook, MD.

     Glaucoma Eye Drop Study
    
A Phase I/II Multi-Center, Randomized, Double-Masked, Placebo-Controlled, Dose-Escalation Study to
     Evaluate the Tolerability, Safety, Pharmacokinetics, and Pharmacodynamics (Efficacy) of Chronic Twice-
     Daily Topical Monocular Application of INO-8875 Ophthalmic Formulation in Adults with Ocular
     Hypertension or Primary Open-Angle Glaucoma-  Malik Y Kahook, MD.

 

Dry Eyes:

     Artificial Tear After Cataract Surgery Study
    
Efficacy Evaluation of Systane® Ultra in Patients Scheduled for Cataract Surgery - Richard S Davidson,
     MD
.

 

Wet Macular Degeneration:

     Combination Injection for New Wet Macular Degeneration
    
A Phase 2, Randomized, Double-masked, Controlled Trial to Establish the Safety and Efficacy of
     Intravitreous Injections of D10030 (Anti-PDGF peglated aptamer) Given in Combination with Lucentis in
     Subjects with Neovascular AMD-  Naresh Mandava, MD.


     Injection for Wet Macular Degeneration and Vitreomacular Adhesion

     A Randomized, Sham-Injection Controlled, Double-Masked, Multicenter Trial of Ocriplasmin Intravitreal
     Injection for Treatment of Focal Vitreomacular Adhesion in Subjects with Exudative Age-Related Macular
     Degeneration (AMD)- Scott Oliver, MD.

Glaucoma:

     Glaucoma Educator Study

     Effect of Glaucoma Educators on Adherence to Prescribed Therapeutic Regimens in Glaucoma Patients-
     Malik Y Kahook, MD.

     Pulmonary Hypertension Study

     Incidence of Nerve Fiber Layer Abnormalities in Patients with Pulmonary Artery Hypertension Using 
     Optical Coherence Tomography - Malik Y Kahook, MD.

     Optic Nerve Imaging Comparison Study

     Comparison of Ocular Imaging Between Time-Domain And Spectral-Domain Ocular Coherence
     Tomography - Malik Y Kahook, MD.

     Tear Analysis Study

     Analysis of Human Tear Proteins: A Pilot Study to Describe the Tear Film Proteome of Patients
     Undergoing Ophthalmic Examination - Malik Y Kahook, MD.

     Ocular Disease and Mental Health Study

     Cognition and Mental Health Among Adults with Eye Disease - Malik Y Kahook, MD.

 

Diabetic Macular Edema:

     RISE Study

     A Phase 3, Double-Masked, Multicenter, Randomized, Sham Injection-Controlled Study of the Efficacy
     and Safety of Ranibizumab Injection in Subjects with Clinically Significant Macular Edema with Center
     Involvement Secondary to Diabetes Mellitus - Jeffrey Olson, MD.

 

Wet Macular Degeneration:

     HARBOR Study

     A Phase III, Double-Masked, Multicenter, Randomized, Active Treatment-Controlled Study of the
     Efficacy and Safety of 0.5mg and 2.0 mg Ranibizumab Administered Monthly or on an as-needed Basis
     (PRN) in Patients With Subfoveal Neovascular Age-Related Macular Degeneration - Scott Oliver, MD.

 

Shingles and Cataract Surgery: 

      Varicella zoster virus (VZV) in saliva of patients with nonspecific eye pain and reactivation in patients
      as a consequence of cataract surgery -  Richard S. Davidson, MD.  

 

Participant Information:
We appreciate your interest in Clinical Research at the University of Colorado, Department of Ophthalmology.   If you are interested in any of our Currently Enrolling studies, please contact Mary Preston at 720-848-2035.   

All clinical research is reviewed by an Institutional Review Board.  Colorado Multiple Institutional Review Board (COMIRB) is an excellent resource for information about participating in clinical trials.  Please visit their web site:  http://www.ucdenver.edu/academics/research/AboutUs/comirb/research-subjects/Pages/research-subjects.aspx

 

Other resources:

http://clinicaltrials.gov/
http://www.wirb.com/content/research_subjects.aspx 
http://health.nih.gov/ 
 

Department of Ophthalmology
University of Colorado Denver
Anschutz Medical Campus
1675 Aurora Court, Mail Stop F-731
Aurora, CO  80045

Phone: (720) 848-2035
Fax: (720) 848-4670

e-mail: mary.preston@ucdenver.edu

 

Medical Emergency:

720-848-2020
After hours/weekends:  303-281-8079