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RESEARCH & CLINICAL TRIALS

Saving sight through advanced treatment approaches


 


Glaucoma:

     Neovascular Glaucoma Study 
     Use of Intravitreal Aflibercept for Neovascular Glaucoma - Malik Kahook, MD.

     Eye Pressure Measurement Study 
     Tolerability and Functionality of a Wireless 24 Hour Ocular Telemetry Sensor in African-American
     Glaucoma Patients - Leonard Seibold, MD.

     Trabeculectomy Study 
     Occlusion Prevention for Trabeculectomy Procedures Using Combination Ranibizumab and Mitomycin
     C (MMC) During Surgery (OCTOPUS STUDY) - Malik Y Kahook, MD.

     Effect of Topical Steroid Drops on Blood Glucose
     Effects and comparison of commonly used regimen of Prednisolone acetate 1% ophthalmic drops on
     blood glucose levels in non-diabetic and diabetic subjects - Mina Pantcheva, MD.

     Glaucoma and cataract surgery (Glaukos)
     Post-approval study of the Glaukos iStent Trabecular Micro-bypass Stent System in conjunction
     with cataract surgery - Leonard Seibold, MD.


Retina:

     Radiation & Choroidal Melanoma
     A prospective pilot study of surgical radiation shielding with vitrectomy and silicone oil tamponade, for
     the prevention of radiation-induced ocular injury in the treatment of choroidal melanoma with
     radioactive Iodine-125 plaque brachytherapy - Scott Oliver, MD.

     Wet Macular Degeneration (Ophthotech)
     Intravitreous administration of Fovista (anti PDGF-B) administered in combination with Lucentis
     compared to Lucentis monotherapy in patients with subfoveal neovascular age-related macular
     degeneration - Naresh Mandava, MD.


Oculoplastics:
     Tears and Eyelid Surgery Study
     Changes in Tear Film Osmolarity After Eyelid Surgery - Eric Hink, MD.
 

     Thyroid Eye Disease (RiverVision)
     Placebo-controlled study of an insulin-like growth factor-1 receptor (IGF-1R) antagonist antibody
     administered every 3 weeks by intravenous infusion in patients suffering from active thyroid eye
     disease - Eric Hink, MD.

 

Neuro-ophthalmology:

     Acute Optic Neuritis
     Neuroprotection with ACTH for acute optic neuritis with onset of symptoms within 12 days of current
     episode - Jeffrey Bennett, MD.  Study coordinator: Ruth Johnson 303-724-7885


Glaucoma:

     Glaucoma eye drop (Bausch & Lomb)
     Comparison of safety and efficacy of  latanoprostene bunod ophthalmic solution with timolol maleate
     ophthalmic solution for open-angle glaucoma or ocular hypertension - Leonard Seibold, MD

     Glaucoma eye drop (Allergan)
     Evaluation of Bimatoprost 0.01% and Bimatoprost 0.03% in patients with glaucoma or ocular
     hypertension - Malik Kahook, MD.

Cornea/External Disease:

     Dry eyes (R-Tech Ueno)
​     Placebo-controlled study of recombinant human serum albumin (rHSA) for treatment of severe dry
     eye - Richard Davidson, MD.


Participant Information:

We appreciate your interest in Clinical Research at the University of Colorado, Department of Ophthalmology.   If you are interested in any of our Currently Enrolling studies, please contact Mary Preston at 720-848-2035.   

All clinical research is reviewed by an Institutional Review Board.  Colorado Multiple Institutional Review Board (COMIRB) is an excellent resource for information about participating in clinical trials.  Please visit their web site:  http://www.ucdenver.edu/academics/research/AboutUs/comirb/research-subjects/Pages/research-subjects.aspx

 

Other Resources:

http://clinicaltrials.gov/
http://www.wirb.com/Pages/ResearchSubjects.aspx  
http://health.nih.gov/ 
http://www.ucdenver.edu/academics/colleges/medicalschool/research/Pages/ClinicalTrials.aspx
 


Department of Ophthalmology
University of Colorado Denver
Anschutz Medical Campus
1675 Aurora Court, Mail Stop F-731
Aurora, CO  80045

Phone: (720) 848-2035
Fax: (720) 848-4670

e-mail: mary.preston@ucdenver.edu

 

Medical Emergency:

720-848-2020
After hours/weekends:  303-281-8079