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Translational Clinical Research in the Department of Neurosurgery


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Eligibility and Information
Brain Tumor Surgery, Drug (interventional)A Phase III Clinical Trial Evaluating DCVax®-L, Autologous Dendritic Cells Pulsed with Tumor Lysate Antigen for the Treatment of Glioblastoma Multiforme (GBM)Kevin O. Lillehei, MD
Monica Robischon, RN 720-848-0661
Brain Tumor Drug, Device (interventional)A Prospective, Multi-center Trial of NovoTTF-100A Together With Temozolomide Compared to Temozolomide Alone in Patients With Newly Diagnosed GBM.Doug Ney, MD
Monica Robischon, RN 720-848-0661
Brain Tumor Drug, Radiation (interventional)Randomized Phase II Trial of Concurrent Bevacizumab and Re-Irradiation versus Bevacizumab Alone as Treatment for Recurrent GlioblastomaLaurie Gaspar, MD
Monica Robischon, RN 720-848-0661
Brain Tumor Drug (interventional)A Phase II Study of Rindopepimut/GM-CSF in Patients With Relapsed EGFRvIII-Positive GlioblastomaDenise Damek, MD
Monica Robischon, RN 720-848-0661
Brain Tumor ObservationalFrailty as a Predictor of Neurosurgical Outcomes in Brain Tumor PatientsD. Ryan Ormond, MD
Jen Maitlen, RN 303-724-1995
Brain Injury Device (interventional)Physiological Effects of Intrathoracic Pressure Regulation in Patients With Decreased Cerebral Perfusion Due to Brain Injury or Intracranial PathologyRobert Neumann, MD
Jen Maitlen, RN 303-724-1995
Brain Surgery BioBankingCentral Nervous System Biorepository ProtocolKevin O. Lillehei, MD
Jen Maitlen, RN 303-724-1995
Neuropsychology ObservationalUniversity of Colorado School of Medicine Neuropsychology DatabaseBrian Hoyt, PhD
Jen Maitlen, RN 303-724-1995
Electrophysiology during Deep Brain Stimulation Surgery (Research)Using Parkinson’s disease to study the role of Substantia nigra pars reticulata in movement initiation and perception Aviva Abosch, MD, PhD
Pamela David Gerecht, PhD 303-724-4134
Electrophysiology during Deep Brain Stimulation Surgery (Research)Local Field Potentials Recorded from Deep Brain Stimulating Electrodes Implanted for the Treatment of Parkinson’s Disease, Essential Tremor or DystoniaAviva Abosch, MD, PhD
Pamela David Gerecht, PhD 303-724-4134

Clinical Trials

  
  
  
Eligibility and Information
A Phase III Clinical Trial Evaluating DCVax®-L, Autologous Dendritic Cells Pulsed with Tumor Lysate Antigen for the Treatment of Glioblastoma Multiforme (GBM)Brain Tumor Surgery, Drug (interventional)Kevin O. Lillehei, MD
Monica Robischon, RN 720-848-0661
A Prospective, Multi-center Trial of NovoTTF-100A Together With Temozolomide Compared to Temozolomide Alone in Patients With Newly Diagnosed GBM.Brain Tumor Drug, Device (interventional)Doug Ney, MD
Monica Robischon, RN 720-848-0661
Randomized Phase II Trial of Concurrent Bevacizumab and Re-Irradiation versus Bevacizumab Alone as Treatment for Recurrent GlioblastomaBrain Tumor Drug, Radiation (interventional)Laurie Gaspar, MD
Monica Robischon, RN 720-848-0661
A Phase II Study of Rindopepimut/GM-CSF in Patients With Relapsed EGFRvIII-Positive GlioblastomaBrain Tumor Drug (interventional)Denise Damek, MD
Monica Robischon, RN 720-848-0661
Physiological Effects of Intrathoracic Pressure Regulation in Patients With Decreased Cerebral Perfusion Due to Brain Injury or Intracranial PathologyBrain Injury Device (interventional)Robert Neumann, MD
Jen Maitlen, RN 303-724-1995


Clinical Research

  
  
  
Eligibility and Information
Frailty as a Predictor of Neurosurgical Outcomes in Brain Tumor PatientsBrain Tumor ObservationalD. Ryan Ormond, MD
Jen Maitlen, RN 303-724-1995
Central Nervous System Biorepository ProtocolBrain Surgery BioBankingKevin O. Lillehei, MD
Jen Maitlen, RN 303-724-1995
University of Colorado School of Medicine Neuropsychology DatabaseNeuropsychology ObservationalBrian Hoyt, PhD
Jen Maitlen, RN 303-724-1995
Using Parkinson’s disease to study the role of Substantia nigra pars reticulata in movement initiation and perception Electrophysiology during Deep Brain Stimulation Surgery (Research)Aviva Abosch, MD, PhD
Pamela David Gerecht, PhD 303-724-4134
Local Field Potentials Recorded from Deep Brain Stimulating Electrodes Implanted for the Treatment of Parkinson’s Disease, Essential Tremor or DystoniaElectrophysiology during Deep Brain Stimulation Surgery (Research)Aviva Abosch, MD, PhD
Pamela David Gerecht, PhD 303-724-4134

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