Skip to main content
Sign In
 

Toxicology Research


Medical toxicologists participate in a wide array of research areas from pharmaceuticals to public health to basic sciences. Examples of medical toxicology research include:

  • Evaluation of the toxicological and therapeutic profile of novel drugs
  • Epidemiologic studies of novel exposures, such as drugs of abuse, envenomation, and household products
  • Basic sciences research into the cellular and genetic mechanisms of toxicity and therapeutic effects
  • Studying the effects of policy changes and public health interventions that may affect drug overdose

 Hoppe, Jason

The Use of Prescription Drug Monitoring Programs and Geographic Information Systems to Identify Communities at Risk of Prescription Opioid Overdose Fatalities
 
Funding Agency: Emergency Medicine Foundation (EMF)
 
Funding Period: July 1st 2013- June 30th 2014
 
Aim:  The purpose of this research is to use death records, Colorado’s Prescription Drug Monitoring Program, and geographic information systems (GIS) to identify communities at risk of prescription opioid overdose.
1

 Monte, Andrew

Genotype-Phenotype Discordance in Polypharmacy Aging Patients
 
Funding Agency: Department of Emergency Medicine Pilot Grant
 
Funding Period: March 1st 2014- February 28th 2015
 
Aim:  The goal of this research projects is to Utilize genotyping and phenotyping of the drug-metabolizing enzyme cytochrome 2D6 (CYP2D6) to improve drug therapy in polypharmacy patients.
 
An Integrated Approach to Personalized Medicine
 
Funding Agency: School of Medicine, Geriatrics
 
Funding Period: July 1st 2013-June 30th, 2015
 
Aim:  This research project integrates clinical, genomic, cytochrome metabolism phenotype, and metabolomic factors to develop a model that predicts systolic blood pressure decline due to metoprolol.
 
Genotype-Phenotype Discordance in Polypharmacy Aging Patients
 
Funding Agency: Department of Emergency Medicine, University of Colorado Denver
 
Funding Period: March 1st 2014- February 28th 2015
 
Aim: The utilization genotyping and phenotyping of the drug-metabolizing enzyme cytochrome 2D6 (CYP2D6) to improve drug therapy in polypharmacy patients.
2