Prediction of Acute Mountain Sickness Using a Blood-Based Test
Funding Agency: Department of Defense (DMDRP)
Fundinbg Period: January 2011 - November 2014
Aim: The design of an easy-to-use, cost-effective test that accurately predicts whether or not someone is likely to develop acute mountain sickness (AMS) when they travel to high altitudes.
AltitudeOmics: The Basic Biology of Human Acclimatization To High Altitude
Funding Agency: Department of Defense (DMDRP)
Funding Period: January 2011 - June 2014
Aim: The advancement of high-altitude medical research by discovering the basic molecular mechanisms of acclimatization that protect soldiers from high-altitude illness.
2Physician Screening of Older Drivers: Decision Rules for Geriatric Injury Prevention
Funding Agency: National Institutes of Health (NIH): National Institute on Aging (NIA)
Supplemental Funding from: American Foundation on Aging Research (AFAR)
Funding Period: August 15th 2013- May 31st 2018
Aim: The application of the model of a clinical decision rule to a public health intervention, through tiered assessment of brief older driver screening in ambulatory care settings followed by referral for more comprehensive testing.
Emergency Department Suicide Screening and Intervention Trial (EDSSIT)
Funding Agency: University of Massachusetts via National Institutes of Health (NIH)
Funding Period: September 30th 2009- May 31st 2014
Aim: The test of the feasibility of a standard screening instrument for depression and suicidal ideation in an emergency department and estimating the frequency of suicidal ideation in individuals presenting to the ED for problems other than mental health.
Pre-planning for developing a long-term multi-site prospective cohort study to better understand senior drivers
Funding Agency: Columbia University via AAA Foundation
Funding Period: October 1st 2013-current
Aim: The AAAFTS Senior Driver Cohort Study project is designed to generate empirical evidence for understanding the dynamics, mechanisms, determinants, and consequences of mobility in senior drivers and for developing effective interventions to ensure safe mobility for older people. With a prospective cohort design, the AAAFTS Senior Driver Cohort Study will involve enrolling a sample of at least 3,000 active drivers from five states located across the U.S. and following them for a minimum of five years.
12Patient Navigation Programs to Improve Care for Medicaid-Enrolled Frequent ED Users
Funding Agency: Colorado Clinical and Translational Sciences Institute KL2
Funding Period: December 1st 2013-November 30th 2015
Aim: The aim of this KL2 project is to gather of information from emergency department patients, providers, and navigators on factors associated with a successful patient navigation outcome (i.e., reducing the number of ED visits) and identifying subpopulations of Medicaid-enrolled frequent ED users who benefit from patient navigation services.
15Vitamin D and Immunosenescence in Older Long-Term Care Residents
Funding Agency: National Institutes of Health (NIH): National Institute on Aging (NIA)
Supplemental Funding from: American Foundation on Aging Research (AFAR)
Funding Period: September 15th 2011- May 31st 2014
Aim: The research goals of this K23 Award are to evaluate the role of vitamin D supplementation in 1) prevention of acute respiratory infection and 2) immune responses to influenza and varicella zoster virus (shingles) vaccine in older long-term care residents.
Prevention and Early Treatment of Acute Lung Injury Network: Colorado PETAL Clinical Center
Funding Agency: National Institutes of Health (NIH): National Heart, Lung, and Blood Institute (NHLBI)
Funding Period: June 14th 2014- April 30th 2021
Aim: The goal of this project is to participate in the selection and conduct of clinical trials for the early treatment of acute lung injury and prevention in high-risk populations such as those with severe sepsis. This clinical center includes two academic and four community hospitals in the greater Denver area.
3
The Use of
Prescription Drug Monitoring Programs and Geographic Information Systems to
Identify Communities at Risk of Prescription Opioid Overdose Fatalities
Funding Agency: Emergency Medicine
Foundation (EMF)
Funding Period: July 1st 2013-
June 30th 2014
Aim: The purpose of this research is to use death
records, Colorado’s Prescription Drug Monitoring Program, and geographic
information systems (GIS) to identify communities at risk of prescription
opioid overdose.
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Genotype-Phenotype Discordance in Polypharmacy Aging
Patients
Funding Agency: Department of Emergency
Medicine Pilot Grant
Funding Period: March 1st 2014-
February 28th 2015
Aim: The goal of this research projects is to Utilize
genotyping and phenotyping of the drug-metabolizing enzyme cytochrome 2D6
(CYP2D6) to improve drug therapy in
polypharmacy
patients.
An Integrated Approach to Personalized Medicine
Funding Agency: School of Medicine,
Geriatrics
Funding Period: July 1st
2013-June 30th, 2015
Aim: This research project integrates clinical,
genomic, cytochrome metabolism phenotype, and metabolomic factors to develop a
model that predicts systolic blood pressure decline due to metoprolol.
Genotype-Phenotype Discordance in Polypharmacy Aging
Patients
Funding Agency: Department of Emergency
Medicine, University of Colorado Denver
Funding Period: March 1st 2014-
February 28th 2015
Aim: The utilization genotyping
and phenotyping of the drug-metabolizing enzyme cytochrome 2D6 (CYP2D6) to
improve drug therapy in polypharmacy patients.
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Demonstrating the Effectiveness of an African
Emergency First Aid Responder System
Funding Agency: Emergency Medicine Foundation
(EMF)
Funding Period: July 1st 2014-
June 30th 2015
Aim: The overarching objective of this study is to
provide initial evidence that a community-based Emergency First Aid Responder
(EFAR) program in sub-Sahara Africa (SSA) enhances the effectiveness and
outcomes of the local emergency care system.
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Efficacy and Utility of Continuous
Electroencephalography in Patients Surviving Cardiac Arrest
Funding Agency: University of Colorado
Hospital
Funding Period: August 1st 2013-August
1st 2014
Aim: The use of Lean management
strategies to optimize the use of continuous electroencephalography (cEEG)
technology in the post-cardiac arrest setting
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Prediction of Acute Mountain Sickness Using a
Blood-Based Test
Funding Agency: Department of Defense (DMDRP)
Funding Period: January 2011 - December 2015
Aim: The design of an easy-to-use,
cost-effective test that accurately predicts whether or not someone is likely
to develop acute mountain sickness (AMS) when they travel to high altitudes.
AltitudeOmics: The Basic Biology of Human
Acclimatization To High Altitude
Funding Agency: Department of Defense (DMDRP)
Funding Period: January 2011 - July 2014
Aim: The advancement of high-altitude medical
research by discovering the basic molecular mechanisms of acclimatization that
protect soldiers from high-altitude illness.
Rapid Acclimatization to Hypoxia at Altitude
Funding Agency: DARPA --- PI: Irwin, D,
Co-PI: Roach, R.
Funding Period: December 2012 - December 2015
Aim: The advancement of high-altitude medical
research by discovering novel preventive measures for acute mountain sickness.
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Integration of an Audience Response System into
Simulation-Based Training: An Educational
Technology Enhancement
Funding Agency: Society for Academic
Emergency Medicine (SAEM)
Funding Period: December 1st
2014- November 30th 2016
Aim: The completion of a
mixed-methods study to evaluate a novel technique for simulation observer engagement,
publication and dissemination of results within the simulation, emergency
medicine, and graduate medical education communities
9
Bridges to Care
Funding Agency: Metro Community Provider
Network (MCPN)
Funding Period: July 1st 2013- June 30th
2015
Aim: The identification of high
frequency utilizers of the emergency department and connect them to intensive
community services and establishing them in medical homes that coordinate their
care to minimize costs and return visits to the emergency department.
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