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The Department of Dermatology deals with all aspects of the biology and diseases of the skin.

Department of Dermatology
 

Qinghong Zhang, PhD


Dr. Qinghong Zhang
Associate Professor of Dermatology
University of Colorado School of Medicine
Denver Veterans Affairs Medical Center
 

Dr. Qinghong Zang earned her Ph.D. in physiological chemistry from the University of Wisconsin, Madison in 1997. Prior to that, she received a Bachelor of Science in 1991 from the University of Science & Technology of China. In addition, she has accumulated more than three years of post-doctoral education at the Vollum Institute in Oregon. As a teacher, she has served as a lecturer in Cancer Biology and a Mentor for a number of PhD students. Presently, she serves as an Assistant Professor of Dermatology and Pathology at the University of Colorado.

Qinghong Zhang’s research focuses on understanding the dynamic changes of the transcriptional network in skin. Transcriptional regulation governs a broad spectrum of cellular activities: cell proliferation, differentiation, migration, apoptosis, and metabolism. She and her team are interested in elucidating the molecular mechanisms underlying transcriptional regulation in response to physiological and pathological signals. Particularly, their research over the past decade has focused on CtBP, a transcriptional co-repressor, and has uncovered a unique function of this protein as a redox-sensor in transcription control. This function allows cells to couple the metabolic status with gene expression in skin biology and cancer development.

Based on this research, therapeutics for skin diseases and wound healing are in development. They have identified a biologic agent capable of topical application for the treatment and/or prevention of psoriasis in a mouse model. The agent’s use in other applications is currently being evaluated.