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University of Colorado Cancer Center

University of Colorado Cancer Center, A National Cancer Institute-designated Comprehensive Cancer Center
 

Tissue Biobanking & Processing Shared Resource


The Tissue Biobanking and Processing Shared Resource (TBPSR) supports cancer research by insuring investigators have access to high quality tissue and body fluid specimens annotated with appropriate clinicopathologic and outcomes data to facilitate research into the causes of cancer.

Services

The TBPSR provides personnel and expertise for biospecimen collection, processing and distribution; laser capture micro dissection (LCM); creation of tissue microarrays, and imaging and image analysis platforms.

The facility has more than 12,000 square feet of total workspace with 100 freezer bays and is fully equipped with an Arcturus XT LCM instrument with IF and UV capabilities, three Beecher Tissue Arrayers, an Aperio XT and two Syncroscopy tissue imaging systems and supporting computer systems.

Objectives

  • To procure, process and store human tissues and body fluid specimens using customized, quality controlled, and documented best practice procedures and to provide these biospecimens, properly triaged for individual research project needs and CU Cancer Center investigators to meet the objectives of their research.
  • To perform special processing techniques on archival tissue specimens including laser capture micro dissection (LCM) and creation of tissue microarrays (TMAs) as needed to meet the objectives of member projects.
  • To provide computer assisted imaging/image analysis with pathological annotation of tissue samples in collaboration with the Molecular Pathology Shared Resource (MPSR) to assist investigators with non-biased interpretation of morphological or immunohistochemical data.
  • To maintain a comprehensive, prospective and interactive database with detailed de-identified clinical and pathologic data in collaboration with Research Informatics Shared Resource.