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University of Colorado Cancer Center

University of Colorado Cancer Center, A National Cancer Institute-designated Comprehensive Cancer Center
 

Small Animal Imaging Services


A major goal of the small animal imaging program is establishment of novel imaging approaches to cancer and cancer experimental therapeutics using animal models and pharmacodynamic endpoints. State-of-the-art imaging facilities are extremely expensive and require advanced technical personnel.

Our facility is fully equipped for magnetic resonance imaging and proton spectroscopy (MRI/ MRS) studies on small animals. All 18FDG-PET and microCT protocols are available.

Services:

Equipment:

  • Small Animal Bruker 4.7 Tesla MRI scanner
  • Siemens Inveon microCT scanner, used mostly for bone scans and lung tumors. Spatial resolution up to 50 microns.
  • Siemens Inveon microPET scanner (field of view 12 cm allowing for one-bed position for the whole-body mouse scan)
  • Three volume transmitter/ receiver coils of different diameters (from 22 to 68 mm diameters)
  • Bruker computer platform is equipped with a high-performance MR-workstation X2000 for use with Bruker MR software (NMR SUITE and PARAVISIONTM 3.0). The PC is configured with Intel Pentium 1.5 Hz, 1 Gbyte RAM, SCSI Controller Adaptec 29160, 73 GByte Disk, Red Hat LINUX, 20” TFT LCD monitor with graphics resolution of 12801024, HP printer, Ethernet card etc.
  • For CT, a high speed imaging processor (COBRA) is available.
  • Anesthesia machines, physiological monitoring system, warming pads and fans, as well as other additional accessories are available in the animal preparation room.