Specialty:
Melanoma Research, Skin Cancer, Biorepository Sciences,
Cancer Biology, Genomics
Location:
University of Colorado Anschutz Medical Campus, Division of
Medical Oncology, School of Medicine
Prerequisites:
Must have completed one year of college
Number of Openings: 1
Program Objective:
To investigate the
Biology of cancer cells in
tumorigenesis, progression, and therapeutic resistance in melanoma.
Genotyping
melanoma tumors for somatic mutations.
Melanoma and squamous cell carcinoma
biomarkers for the diagnosis and prediction of disease progression, treatment
response.
RNA desiccation, expression profiling.
Whole genome/exome
sequencing for next generation molecular studies.
Program Description:
The main focus of our current research is:
To
characterize melanoma tumors for somatic mutations
To
study biological roles of several inflammatory cytokines (particularly
IL-1, IL-37 and AAT) in the progression of human malignant melanoma
Annotate
plasma, serum, WBC, DNA and RNA samples
To
identify melanoma-related and host response-related biomarker profiling
from blood/tumor from melanoma, squamous cell, and basal cell cancer
patients