Specialty:
Molecular Oncology
Location:
University of Colorado Anschutz
Medical Campus
Prerequisites:
The student must have completed two
years of college and have at least a small amount of biochemistry lab training.
Number of Openings: 1
Objective:
The overall goal of this project is
to understand the molecular mechanisms of chromatin-interacting long noncoding
RNAs in gene silencing that contribute to cancer progression.
Description:
The student will initially work
closely with members of the laboratory to then develop a discrete project
studying the biochemistry and molecular biology of a cancer-associated RNA that
transits through the nucleus to repress gene expression.
Our work focuses on
certain members of this trans-acting RNA family that can either contribute to
the pathways that defend against cancer, or have been show to drive tumor
development and metastasis.