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University of Colorado Cancer Center

University of Colorado Cancer Center, A National Cancer Institute-designated Comprehensive Cancer Center

Lynn Heasley, PhD



Signal pathways mediating autocrine growth of cancer cells


Lung Cancer, Head and Neck Cancer


University of Colorado Anschutz Medical Campus, Department of Craniofacial Biology


Must have completed one year of college

Openings: 1

Program Objective:

To use molecular biology and pharmacological inhibitors to identify specific growth factors, their receptor tyrosine kinases and signaling enzymes mediating autocrine growth of lung cancer and head and neck cancer cell lines.

Program Description:

Students will employ the following laboratory procedures:

  1. cell culture of human lung cancer and/or head and neck cancer cell lines;
  2. transfection experiments with expression vectors to over-express or silence specific gene products such as growth factors and growth factor receptors;
  3. perform assays to assess the effect of molecular perturbations or inhibitors on MAP kinase signaling, cell proliferation and anchorage-independent growth.  


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