Genitourinary (GU) malignancies
University of Colorado Anschutz Medical Campus
Must have completed two years of college
Number of Openings: 1
Develop new therapies for the treatment of urologic cancers
Our laboratory is exploring multiple new methods for treating urologic
cancers. Bladder cancer is a significantly neglected cancer in terms of
research attention. While it is the sixth most common cancer in humans, there
have been no major treatment improvements in the last couple of decades.
In superficial bladder cancer, we continue to use the only modestly
effective treatments discovered in the 1970’s. Our work in looking for new
treatment approaches includes integration of nano-technology, toxic fusion
protein therapy and small molecule inhibitors testing. Another major thrust in our
group is the use of microRNA expression to predict and better understand
traditional chemotherapy resistance in bladder cancer.
We also have active research projects in the characterization and treatment
of prostate cancer, with potential opportunities in that area as well. We
are currently examining the causes of resistance to highly active androgen
therapy. Past and some ongoing projects in prostate cancer have included
the evaluation of natural products to treat prostate cancer.
Opportunities for summer students include bench work focused on the
evaluation of new treatments with a focus on cell culture technique and cell
viability. Other techniques such as QT-PCR and Western blotting may be
utilized as needed.