Breast Oncology, Developmental Therapeutics
CU Anschutz Medical Campus
Positions Available: 1
The major goals of ongoing projects are (a) to evaluate novel targeted anticancer agents against preclinical models of breast cancer and (b) to identify candidate biomarkers predictive of sensitivity.
We use techniques such as proliferation assays, apoptosis assays, cell cycle analysis and western blots for signaling molecules to evaluate the activity of targeted drugs in breast cancer. We then use genomic analysis such as gene expression profiling to identify differences between our sensitive and resistant cell lines.
Students will: a) perform tissue culture, b) carry-out proliferation assays, apoptosis assays and cell cycle analysis, c) analyze and organize data for presentation, and d) interpret and discuss results according to the literature.