Cell growth, death and senescence, signaling pathways and experimental and molecular therapeutics
Lung Cancer, Medical Oncology
University of Colorado Anschutz Medical Campus
Must have completed two years of college
To learn experimental techniques used in basic cancer research, especially those employing new treatment modalities to interrupt the growth factor pathways of lung cancer.
Students will be involved with a variety of laboratory procedures, including: 1) cell culture of human lung cancer cell lines; 2) assays to assess treatment cytotoxicity: growth curves, clonogenic assays, and MTT assay; 3) treatment of cell lines with novel molecularly targeted agents or shRNA alone and in combination that target growth factor pathways critical to tumor cell survival; and 4) studies to determine the mechanism of action of candidate agents with potential therapeutic utility in lung cancers (Western blots).