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Sex Differences in the Cardiovascular Consequences of Diabetes Mellitus​: A Scientific Statement From the American Heart Association​. Contributions by CWHR researchers Drs. Amy Huebschmann, Jane EB Reusch and Judith RegensteinerRead the full statement

Adolescent girls with type 2 diabetes who became pregnant while participating in the TODAY study experienced a high rate of pregnancy loss and complications... Read the full article
Characterization of subgroups of heart failure patients with preserved ejection fraction with possible implications for prognosis and treatment response... Read the full article​​

​Physical Inactivity is the Top Factor for Heart Disease in Women - British Journal of Sports Medicine

Physical inactivity is the top factor for heart disease in women.pdfPhysical inactivity is the top factor for heart disease in women.pdf


Dr. Colleen Julian, CWHR Researcher:

Julian CG, Subudhi AW, Hill RC, Wilson MJ, Dimmen AC, Hansen KC, and RC Roach. Exploratory proteomic analysis of acute mountain sickness and hypobaric hypoxia in humans [2013, JAP; in press]
Julian CG, Yang IV, Browne VA, Vargas E, Rodriguez C, Pedersen BS, Moore LG, and DA Schwartz. Inhibition of peroxisome proliferator receptor gamma (PPARγ): a potential link between chronic maternal hypoxia and impaired fetal growth. [2013, FASEB; in press]
Subudhi AW, Fan J, Evero O, Bourdillon N, Kayser B, Julian CG, Lovering AT, Panerai RB, and RC Roach. AltitudeOmics: Effect of ascent, acclimatization, and re-exposure to 5,260m on cerebral autoregulation. [2013, Exp Physiol; in press]

Sex Differences in Cardiovascular Disease Risk and Exercise in Type 2 Diabetes.pdfSex Differences in Cardiovascular Disease Risk and Exercise in Type 2 Diabetes.pdf

Miller TM, Gilligan S, Herlache LL, Regensteiner JG 
Journal of Investigative Medicine, Volume 60, Number 4, April 2012

​It's Time for Women to Pay More Attention to This Health Concern

Posted: 08/27/2013 10:35 am
If you ask an American woman to list her concerns about disease, breast cancer will almost invariably rank high. Breast cancer awareness in this country is an institution, serving as a banner for the largest series of 5K runs in the world (Race for the Cure) and claiming the month of October for fundraising against the disease across the country. During that month every year, pink ribbons adorn the lapels of politicians and are emblazoned on celebrity T-shirts, and even corporations not exactly associated with health such as Kentucky Fried Chicken line up to sponsor the cause.
Many people have contributed to the effort to make breast cancer awareness mainstream, and they should be lauded. But these campaigns may have had an unintended side effect -- rendering women a bit flat-footed when it comes to even bigger threats to their health. Like breast cancer, heart disease is discussed in gendered terms; it's commonly understood as an affliction that strikes men. But did you know that since 1984, the number of cardiovascular disease-related deaths for females has exceeded those for males?
Heart disease is the leading cause of death for women in the United States, and every year it kills significantly more women than all types of cancers combined.
Today, more than one in three female adults has some form of cardiovascular disease.
Each year, cardiovascular heart disease affects about 380,000 mothers, sisters, daughters, wives and girlfriends. To put that figure into perspective, it's about as many lives as the entire population of Anchorage, Alaska.
Educating women about the causes and ways to prevent and manage heart disease is critical. Awareness is improving -- the number of women who know that heart disease is the leading cause of death has nearly doubled in the last 15 years -- but it's still far from complete, and awareness still lags significantly more among minorities and younger women.
Although men may have more of an association with heart disease, educating them about prevention and management is just as crucial. Heart disease is the leading cause of death for both men and women in the United States, responsible for approximately 1 million deaths annually!

The good news is that there's a great deal that can be done to prevent and reverse heart disease. Healthy lifestyle, knowledge of risk factors, and regular health screenings can dramatically decrease the likelihood of developing heart disease. Increased awareness of how heart disease can develop in the first place can serve as an inspiration to take action toward optimal heart health.

In light of the importance of this cause, we've decided to partner with the American Heart Association (AHA) to help close the knowledge gap. We are true soul mates in this marriage: Both HuffPost and the AHA are passionately committed to promoting ways to improve health and decrease stress. At HuffPost Healthy Living, we have published an abundance of posts with tips on how to take care of your heart -- addressing nutrition, exercise, meditation, yoga, sleep, mindfulness, medical screenings, loving relationships, and many other aspects of optimal heart health.

We have even created a free app called GPS for the Soul that helps you reduce stress by looking at your heart rate and heart rate variability to help assess your level of balance and harmony. The guides within the app help you to course correct if you find yourself in a stressful state vs. a loving, heart-centered state.
Furthermore, a major theme at HuffPost, The Third Metric, is about exploring a definition of success that goes beyond money and power and emphasizes quality-of-life measures such as well-being. Practices such as mindfulness and meditation that we love to discuss at Healthy Living have been demonstrated to support the immune system, reduce stress, and decrease the likelihood of chronic diseases like heart disease.
Now, we are so fortunate to be able to take our heart health coverage to a whole new level thanks to our partnership with the American Heart Association.
Beginning this week, HuffPost and the AHA will be publishing regular blog posts on heart health. We will be hearing from Nancy Brown, the CEO of American Heart Association. I had the absolute pleasure of connecting with Nancy at the Third Metric Conference in June, and we exuberantly shared our concern on the urgent need to educate the public on issues of prevention of cardiovascular disease and stroke. Being passionate about heart health myself, meeting Nancy was like meeting a kindred spirit. Within a few minutes of meeting Nancy, I could tell this was a woman with an abundant heart who is truly on a mission to dramatically affect change in the health of our society. It is an honor to have her voice at The Huffington Post.

Nancy also brings her team of experts who will be blogging on a variety of subjects to help us keep our hearts healthy. Aspects of nutrition, exercise, sleep, and digital health will be presented, and we will be kept up to date with the latest studies so we will have the tools we need to be the best stewards of our cardiovascular system.

We look forward to the day when we see an abundance of red ribbons proudly worn, not simply to raise awareness of heart disease, but also in celebration of improved heart health and lives saved as a result of increased awareness and implementation of heart healthy measures.
2013-08-26-AHA_ASA.jpgThis post is part of a series produced by The Huffington Post and the American Heart Association addressing important, timely topics in heart health and wellness. Heart disease is the No. 1 killer of Americans. American Heart Association CEO Nancy Brown and featured experts will examine the issues related to heart disease and provide information, ideas and insight.

Risk Factor Reduction After Heart Attack - Age, Race, and Gender Matter

New Rochelle, NY, August 22, 2013—Risk factor modification efforts could help reduce the chance of another heart attack and death among the more than 15 million Americans with coronary heart disease. Yet some patients—especially women and minorities—leave the hospital with poorly managed risk factors. An article in Journal of Women’s Health, a peer-reviewed publication from Mary Ann Liebert, Inc., publishers, evaluates cardiac risk factors and management strategies by age, sex, and race among 2,369 patients hospitalized for acute myocardial infarction. The article is available free on the Journal of Women’s Health website.
About 93% of the patients in the study had at least one of the five cardiac risk factors evaluated, including hypertension, hypercholesterolemia, current smoking, diabetes, and obesity. Black patients were much more likely to have multiple risk factors than white patients, and black women had the greatest risk factor burden of any of the subgroups. Differences in risk factor modification efforts based on race were also reported.
Erica Leifheit-Limson, PhD and coauthors from Yale School of Public Health and School of Medicine, and Yale-New Haven Hospital (New Haven, CT), St. Luke's Mid America Heart Institute and University of Missouri-Kansas City (Kansas City, MO), and Emory University Rollins School of Public Health and the School of Medicine (Atlanta, GA) report the study results in the article “Prevalence of Traditional Cardiac Risk Factors and Secondary Prevention Among Patients Hospitalized for Acute Myocardial Infarction (AMI): Variation by Age, Sex, and Race.”
“These findings indicate missed opportunities for both prevention and management of cardiac risk factors, particularly for women and minority patients,” says Susan G. Kornstein, MD, Editor-in-Chief of Journal of Women’s Health, Executive Director of the Virginia Commonwealth University Institute for Women’s Health, Richmond, VA, and President of the Academy of Women’s Health.

​Center for Women’s Health Research Announces Judith and Joseph Wagner Endowed Chair in Women’s Health Research Fund

The Center for Women’s Health Research at the University of Colorado School of Medicine is pleased to announce the creation of the Judith and Joseph Wagner Endowed Chair in Women’s Health Research. The chair is held by Judith G. Regensteiner, PhD, Professor of Medicine at the University of Colorado who is the Co-founder and Director of the Center for Women’s Health Research.

Responding to the dearth of research on women’s health issues, Dr. Regensteiner co-founded the Center for Women’s Health Research in 2002. Her research expertise, for which she is internationally known, is in the areas of women’s health, diabetes and cardiovascular disease. Her research in diabetes in particular is focused on gaining understanding of the cardiovascular effects of type 2 diabetes so that optimal treatments can be sought. She has been Principal Investigator or Co-Investigator of several current and previous large grants in type 2 diabetes and peripheral arterial disease funded by NIH and the American Diabetes Association. She has published extensively in these areas and has received honors including the Elizabeth Gee Lectureship Award, the Department of Medicine Ph.D. Teaching and Research Award and the Henry Christian award for outstanding cardiovascular research from the American Federation for Medical Research.  Dr. Regensteiner is currently also Principal Investigator of the National Institutes of Health’s Building Research Careers in Women’s Health (BIRCWH) grant, serves on the Advisory Board of Office of Research in Women’s Health at the NIH, and is particularly passionate about mentoring the next generation of physician/scientists.
Through its focus on recruitment and mentoring of excellent physician scientists committed to women’s health/sex differences research, the Center for Women’s Health Research seeks to accelerate improvements in women’s health by uncovering answers to medical questions relating to cardiovascular disease and diabetes. The $2 million endowed chair is one of the few chairs in women’s health research in the world and is the first at the University of Colorado. Recognizing the significance of this historic milestone in women’s health research at the University of Colorado, Judith and Joseph Wagner’s lead gift inspired more than forty individuals and foundations in the community to complete funding for the Chair within an eighteen-month timeframe.



Dr. Judy Regensteiner shares her insights about mentoring in the Journal of Women's Health,

"​Best Practices and Pearls in Interdisciplinary Mentoring"

jwh 2012 Best Practices and Pearls in Interdisciplinary Mentoring.pdfjwh 2012 Best Practices and Pearls in Interdisciplinary Mentoring.pdf

​Dr. Amy Huebschmann: Research highlighted in Science Daily

"Exercise Helps Ease Premature Cardiovascular Aging Caused by Type 2 Diabetes"