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Considering Sex as a Biological Variable will be Valuable for Neuroscience Research

The recently implemented NIH policy requiring that grant applicants consider sex as a biological variable in the design of basic and preclinical animal research studies has prompted considerable discussion within the neuroscience community. This article presents reasons to be optomistic that this new policy will be valuable for neuroscience and suggests some ways for neuroscientists to think about incorportaing sex as a variable in their research.   

Sex Differences in the Cardiovascular Consequences of Diabetes Mellitus

Sex Differences in the Cardiovascular Consequences of Diabetes Mellitus​: A Scientific Statement From the American Heart Association​. Contributions by CWHR researchers Drs. Amy Huebschmann, Jane EB Reusch and Judith RegensteinerRead the full statement

​University of Colorado School of Medicine Among Ten Institutions to Receive Grants to Retain Clinical Scientists
The Doris Duke Charitable Foundation announced that the University of Colorado School of Medicine is one of 10 recipients of a $540,000 award, The Fund to Retain Clinical Scientists (DDCF award announcement). The purpose of the Fund to Retain Clinical Scientists is to build upon a growing momentum in the medical research field toward supporting young physician scientists through phases of intense, extraprofessional career obstacles and difficult life transitions. The Center for Women's Health Research Director, Judy Regensteiner, PhD and Anne Libby, PhD will serve as Principal Investigators of this grant, which has been generously matched to total $1 million over 5 years.​​​
CWHR Researcher Publication: Dr. Kristen Nadeau
Adolescent girls with type 2 diabetes who became pregnant while participating in the TODAY study experienced a high rate of pregnancy loss and complications... Read the full article
Reducing body temperature can save neurological functions

Therapeutic hypothermia is effective on patients with `nonshockable’ cardiac arrests. Survivors of cardiac arrest who remain in comas have better survival and neurological outcomes when their body temperatures are lowered, according to new research by Dr. Sarah Perman at the University of Colorado Anschutz Medical Campus. Read the full article

NPR: Fetal Cells May Protect Mom From Disease Long After The Baby's Born

This is a story about two people sharing one body. Maybe even three people. Or four. Back in the late 19th century, a German scientist named Georg Schmorl made a remarkable discovery: Cells from a baby can hide out in a mother's body, after birth... ​Read the full article

CWHR Researcher Publication: Dr. David Kao
Characterization of subgroups of heart failure patients with preserved ejection fraction with possible implications for prognosis and treatment response... Read the full article​​
TIME Magazine: CWHR Researcher Publication: Dr. Kristin Boyle
Kids of obese moms are more likely to be obese, and the latest research suggests that influence may begin in the womb... Read the full article
CDC released new National Diabetes Statistics Report 29.1 million children and adults in the U.S. (9.3% of the population) with diabetes – 8.1 million are undiagnosed.
The CDC has released its new National Diabetes Statistics Report this morning.  The new numbers show there are now 29.1 million children and adults in the U.S. (9.3% of the population) with diabetes – 8.1 million are undiagnosed. An additional 37% of the U.S. adult population has prediabetes – that’s 86 million adults.

Physical Inactivity is the Top Factor for Heart Disease in Women

​Physical Inactivity is the Top Factor for Heart Disease in Women - British Journal of Sports Medicine

Physical inactivity is the top factor for heart disease in women.pdfPhysical inactivity is the top factor for heart disease in women.pdf

Ted Talk - Paula Johnson5/5/2014
Chronicle of Philanthropy

Scientific Leaps Require Donors to Give Bigger.

"Money, we can all agree, matters.  It doesn't buy happiness, but it certainly buys a ton of scientific research of vital importance to human health.  Without that, the pursuit of happiness wouldn't even be possible."  

chronicle article april 2014.pdfchronicle article april 2014.pdf

Low-carb, high-fat diet may not be best for gestational diabetes

Low-carb, high-fat diet may not be best for gestational diabetes

Internal Medicine News - CWHR Researcher Teri Hernandez, RN, PhD:

Colorado research center works to get more women working in science

Judy Regensteiner, Director of the Center for Women's Health Research, was interviewed by by Heather Mills at KDVR about getting and keeping women in science:

Judy Regensteiner, Director of the Center for Women's Health Research, was interviewed by Heather Mills at KDVR about getting and keeping women in science. See the segment here: 2/19/2014
Sex Matters: Drugs Can Affect Sexes Differently

​Sex Matters: Drugs Can Affect Sexes Differently

Lesley Stahl reports on CBS 60 Minutes:

Weight Lifting Linked with Lower Type 2 Diabetes Risk in Women1/17/2014
Dr. Colleen Julian has three articles in press

Dr. Colleen Julian, CWHR Researcher:

Julian CG, Subudhi AW, Hill RC, Wilson MJ, Dimmen AC, Hansen KC, and RC Roach. Exploratory proteomic analysis of acute mountain sickness and hypobaric hypoxia in humans [2013, JAP; in press]
Julian CG, Yang IV, Browne VA, Vargas E, Rodriguez C, Pedersen BS, Moore LG, and DA Schwartz. Inhibition of peroxisome proliferator receptor gamma (PPARγ): a potential link between chronic maternal hypoxia and impaired fetal growth. [2013, FASEB; in press]
Subudhi AW, Fan J, Evero O, Bourdillon N, Kayser B, Julian CG, Lovering AT, Panerai RB, and RC Roach. AltitudeOmics: Effect of ascent, acclimatization, and re-exposure to 5,260m on cerebral autoregulation. [2013, Exp Physiol; in press]
Opinion: Despite good intentions, women not achieving good health10/30/2013
Five questions for Judith Regensteiner

​Five questions for Judith Regensteiner:  CU alumna investigates women's health - and helps others do the same.

Racial Differences and Characteristics of Peripartum Cardio Myopathy

​Racial Differences and Characteristics of Peripartum Cardio Myopathy

American College of Cardiology CardioSource VideoNews

It's Time for Women to Pay More Attention to THIS Health Concern

​It's Time for Women to Pay More Attention to This Health Concern

Posted: 08/27/2013 10:35 am
If you ask an American woman to list her concerns about disease, breast cancer will almost invariably rank high. Breast cancer awareness in this country is an institution, serving as a banner for the largest series of 5K runs in the world (Race for the Cure) and claiming the month of October for fundraising against the disease across the country. During that month every year, pink ribbons adorn the lapels of politicians and are emblazoned on celebrity T-shirts, and even corporations not exactly associated with health such as Kentucky Fried Chicken line up to sponsor the cause.
Many people have contributed to the effort to make breast cancer awareness mainstream, and they should be lauded. But these campaigns may have had an unintended side effect -- rendering women a bit flat-footed when it comes to even bigger threats to their health. Like breast cancer, heart disease is discussed in gendered terms; it's commonly understood as an affliction that strikes men. But did you know that since 1984, the number of cardiovascular disease-related deaths for females has exceeded those for males?
Heart disease is the leading cause of death for women in the United States, and every year it kills significantly more women than all types of cancers combined.
Today, more than one in three female adults has some form of cardiovascular disease.
Each year, cardiovascular heart disease affects about 380,000 mothers, sisters, daughters, wives and girlfriends. To put that figure into perspective, it's about as many lives as the entire population of Anchorage, Alaska.
Educating women about the causes and ways to prevent and manage heart disease is critical. Awareness is improving -- the number of women who know that heart disease is the leading cause of death has nearly doubled in the last 15 years -- but it's still far from complete, and awareness still lags significantly more among minorities and younger women.
Although men may have more of an association with heart disease, educating them about prevention and management is just as crucial. Heart disease is the leading cause of death for both men and women in the United States, responsible for approximately 1 million deaths annually!

The good news is that there's a great deal that can be done to prevent and reverse heart disease. Healthy lifestyle, knowledge of risk factors, and regular health screenings can dramatically decrease the likelihood of developing heart disease. Increased awareness of how heart disease can develop in the first place can serve as an inspiration to take action toward optimal heart health.

In light of the importance of this cause, we've decided to partner with the American Heart Association (AHA) to help close the knowledge gap. We are true soul mates in this marriage: Both HuffPost and the AHA are passionately committed to promoting ways to improve health and decrease stress. At HuffPost Healthy Living, we have published an abundance of posts with tips on how to take care of your heart -- addressing nutrition, exercise, meditation, yoga, sleep, mindfulness, medical screenings, loving relationships, and many other aspects of optimal heart health.

We have even created a free app called GPS for the Soul that helps you reduce stress by looking at your heart rate and heart rate variability to help assess your level of balance and harmony. The guides within the app help you to course correct if you find yourself in a stressful state vs. a loving, heart-centered state.
Furthermore, a major theme at HuffPost, The Third Metric, is about exploring a definition of success that goes beyond money and power and emphasizes quality-of-life measures such as well-being. Practices such as mindfulness and meditation that we love to discuss at Healthy Living have been demonstrated to support the immune system, reduce stress, and decrease the likelihood of chronic diseases like heart disease.
Now, we are so fortunate to be able to take our heart health coverage to a whole new level thanks to our partnership with the American Heart Association.
Beginning this week, HuffPost and the AHA will be publishing regular blog posts on heart health. We will be hearing from Nancy Brown, the CEO of American Heart Association. I had the absolute pleasure of connecting with Nancy at the Third Metric Conference in June, and we exuberantly shared our concern on the urgent need to educate the public on issues of prevention of cardiovascular disease and stroke. Being passionate about heart health myself, meeting Nancy was like meeting a kindred spirit. Within a few minutes of meeting Nancy, I could tell this was a woman with an abundant heart who is truly on a mission to dramatically affect change in the health of our society. It is an honor to have her voice at The Huffington Post.

Nancy also brings her team of experts who will be blogging on a variety of subjects to help us keep our hearts healthy. Aspects of nutrition, exercise, sleep, and digital health will be presented, and we will be kept up to date with the latest studies so we will have the tools we need to be the best stewards of our cardiovascular system.

We look forward to the day when we see an abundance of red ribbons proudly worn, not simply to raise awareness of heart disease, but also in celebration of improved heart health and lives saved as a result of increased awareness and implementation of heart healthy measures.
2013-08-26-AHA_ASA.jpgThis post is part of a series produced by The Huffington Post and the American Heart Association addressing important, timely topics in heart health and wellness. Heart disease is the No. 1 killer of Americans. American Heart Association CEO Nancy Brown and featured experts will examine the issues related to heart disease and provide information, ideas and insight.
Risk Factor Reduction After Heart Attack—Age, Race, and Gender Matter

Risk Factor Reduction After Heart Attack - Age, Race, and Gender Matter

New Rochelle, NY, August 22, 2013—Risk factor modification efforts could help reduce the chance of another heart attack and death among the more than 15 million Americans with coronary heart disease. Yet some patients—especially women and minorities—leave the hospital with poorly managed risk factors. An article in Journal of Women’s Health, a peer-reviewed publication from Mary Ann Liebert, Inc., publishers, evaluates cardiac risk factors and management strategies by age, sex, and race among 2,369 patients hospitalized for acute myocardial infarction. The article is available free on the Journal of Women’s Health website.
About 93% of the patients in the study had at least one of the five cardiac risk factors evaluated, including hypertension, hypercholesterolemia, current smoking, diabetes, and obesity. Black patients were much more likely to have multiple risk factors than white patients, and black women had the greatest risk factor burden of any of the subgroups. Differences in risk factor modification efforts based on race were also reported.
Erica Leifheit-Limson, PhD and coauthors from Yale School of Public Health and School of Medicine, and Yale-New Haven Hospital (New Haven, CT), St. Luke's Mid America Heart Institute and University of Missouri-Kansas City (Kansas City, MO), and Emory University Rollins School of Public Health and the School of Medicine (Atlanta, GA) report the study results in the article “Prevalence of Traditional Cardiac Risk Factors and Secondary Prevention Among Patients Hospitalized for Acute Myocardial Infarction (AMI): Variation by Age, Sex, and Race.”
“These findings indicate missed opportunities for both prevention and management of cardiac risk factors, particularly for women and minority patients,” says Susan G. Kornstein, MD, Editor-in-Chief of Journal of Women’s Health, Executive Director of the Virginia Commonwealth University Institute for Women’s Health, Richmond, VA, and President of the Academy of Women’s Health.
Outstanding Research Mentor Award for 2013

Dr. Judy Regensteiner has been chosen by the CU Clinical Science Graduate Program to receive the Outstanding Research Mentor Award for 2013.  This award is based on student nominations that describe the attributes of the person and details examples that make this individual an outstanding mentor

Gender Summit - North America

​Dr. Judy Regensteiner was invited to give a presentation at the Gender Summit – North America, an international research and innovation conference that will be held on November 13-15 2013 in Washington D.C.  Her presentation will focus on her published paper, Best Practices and Pearls in Interdisciplinary Mentoring.

The Summit is being co-convened by the National Science Foundation (NSF), the Natural Sciences and Engineering Research Council of Canada (NSERC - CRSNG), the National Council on Science and Technology of Mexico (CONACYT), US National Institutes of Health (NIH), The Canadian Institutes of Health Research (CIHR), and the UK based NGO, Portia Ltd.
TODAY Study Sounds Alarm Bell for Youth with Type 2 Diabetes

​TODAY Study Sounds Alarm Bell for Youth with Type 2 Diabetes

TODAY Study Sounds Alarm Bell for Youth with Type 2 Diabetes.pdfTODAY Study Sounds Alarm Bell for Youth with Type 2 Diabetes.pdf

Diabetes Caucus Briefing, “Diabetes 101: Disease and Policy Basics.”

Dr. Judy Regensteiner was introduced Tuesday morning by Rep. Diana DeGette at the Rayburn House Office Building.  Dr. Regensteiner was one of three panelists invited to speak at the Diabetes Caucus Briefing, “Diabetes 101: Disease and Policy Basics.”


Exercise Related Research 2013

​Exercise Related Research 2013, by Leah Herlache

WISH_ENDO_Exercise_Related_ Research_2013.pdfWISH_ENDO_Exercise_Related_ Research_2013.pdf

Laura Brown, MD Fetal Programming

​Womb May Hold Secrets to Curbing Obesity, Diabetes

Laura Brown, MD featured in Health Policy Solutions

Successful fundraising effort leads to CWHR Endowed Chair1/31/2013
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