Danny Zipris, PhD
Assistant Professor
BioResources Core Director, The Diabetes and Endocrinology Research Center (DERC)
BioSketch
Publications:
Zipris D., Crow A.R., and Delovitch T.L. (1991). Altered thymic and peripheral T-lymphocyte repertoire precede the development of diabetes in NOD mice. Diabetes. 40:429.
Zipris D., Lazarus A.L., Crow A.R. , Hadzija M, and Delovitch T.L. (1991). Defective thymic T cell activation by Con A and anti-CD3 in autoimmune NOD mice. Evidence for thymic T cell anergy that correlates with the onset of insulitis. J. Immunol. 146:3763.
Rapoport M.J., Jaramillo A., Zipris D., Lazarus A.H., Serreze D.V., Leiter E.H., Cyopick P., Danska J.S., and Delovitch T.L. (1993). IL-4 reverses T cell unresponsiveness and prevents the onset of diabetes in nonobese diabetic mice. J. Exp. Med. 178:87.
Levy L., Claes D.E., Zipris D., and Cohen I.R. (1994). Protection of mice against mycobacterial infection by lymphoid cell vaccination. Isr. J. Med. Sci. 30:22.
Zipris D., Greiner D.L., Malkani S., Whalen B., Mordes J.P., and Rossini A.A. (1996). Cytokine gene expression in islets and thyroids of BB rats: Interferon-g and IL-12p40 mRNA increase with age in both diabetic and insulin treated nondiabetic BB rats. J. Immunol. 156:1315.
Zipris D. (1996). Evidence that Th1 lymphocytes predominate in islet inflammation and thyroiditis in the Biobreeding (BB) rat. J. Autoimmun. 9:315.
Kanaitsuka T., Bortell R., Stevens L.A., Moss J., Sardinha D., Rajan T.V., Zipris D., Mordes J.P., Greiner D.L. and Rossini A.A. (1997). Expression in BALB/c and C57BL/6 mice of Rt6-1 and Rt6-2 ADP-ribosyltransferase that differ in enzymatic activity. C57BL/6 Rt6 is a natural transferase knockout. J. Immunol. 159:2741.
Zipris, D., Mordes J.P., Greiner D.L. and Rossini A.A.. (2000). Animal models of type 1 diabetes: concordances,discordances, lessons. In: Di Mario, U, Leonetti, F, Pugliese, G, Sbriglia, M, and Signore, A, eds. Diabetes in the newmillennium. John Wiley & Sons, Chichester, UK, 1-16, 2000.
Zipris D., Leif J., Deluca D., Lin M.Y., Mordes J.P., Rossini A.A., Greiner D.L. and Whalen B.J. (2001). Fetal thymi from diabetes-prone but not diabetes-resistant BB/Wor rats fail to generate mature ART2+ T-cells in organ culture. Cell. Mol. Biol. 47:65.
Zipris D. and Karnieli E. (2002). A single treatment with IL-4 via retrovirally transduced lymphocytes partially protects against diabetes in BioBreeding (BB) rats. J.O.P 2002 3:76.
Zipris D., Hillebrands J.L., Welsh R.M., Rozing J., Xie J.X., Mordes J.P., Greiner D.L. and Rossini A.A. (2003). Infections that induce autoimmune diabetes in BBDR rats modulate CD4+CD25+ T cell populations. J. Immunol. 170:3592.
Zipris D., Lien E., Xie J.X., Greiner D.L., Mordes J.P., Rossini A.A. (2005). TLR activation synergizes with Kilham rat virus infection to induce diabetes in BBDR rats. J. Immunol. 174:131.
Beaudette-Zlatanova B.C., Whalen B.J., Zipris D., Yagita H., Rozing J., Benjamin C.D., Hunig T., Drexhage H.A., Amari M.J., Leif J., Mordes J.P., Greiner D.L., Sayegh M.H. and Rossini A.A. (2005). Costimulation and Autoimmune Diabetes in BB Rats. Am. J. Transplant. 6(5 Pt 1):894.
Zipris D., Lien E., Xie J.X., Nair A., Greiner D.L., Mordes J.P. and Rossini A.A. (2007). TLR-9 signaling pathways are involved in Kilham Rat Virus-induced autoimmune diabetes in the BBDR rat. J. Immunol. 178:693.
To access a more complete listing of publications, please go to PubMed http://www.ncbi.nlm.nih.gov/PubMed/ and use the search term Barbara Davis Center for Childhood Diabetes or enter individual author names.
Please direct inquiries to specific e-mail addresses listed within individual entries. For all other general Research inquiries, please contact:
kathryn.gray@ucdenver.edu