The Natural History Study is screening relatives of people with type 1 diabetes. The family members can see if they are at risk for developing diabetes.
Who can be screened?
- First degree relatives: brothers, sisters, mothers, fathers, offspring (ages 1-45, inclusive)
- Second degree relatives: cousins, nieces, nephews, ½ brothers and sisters, grandchildren (ages 1-20 inclusive)
Note: the relative with diabetes needs to have been diagnosed before the age of 40 and started on insulin within the first year of diagnosis.
How are relatives screened and for what?
A simple blood test is done looking for diabetes-related autoantibodies. These antibodies may appear years before type 1 diabetes develops. Relatives of people with type 1 diabetes have about a 3-4% chance of testing positive for the antibodies associated with diabetes. There is no cost for this test.
What happens if I do have autoantibodies?
Additional tests will be offered to estimate your chances of developing type 1 diabetes. If you qualify, you may have an opportunity to join a Prevention Study. All research volunteers will be closely monitored for early detection of type 1 diabetes.
Why is the Natural History Study being done?
The Natural History Study is being done to learn more about what causes type 1 diabetes. The study hopes to better define predictors of the disease process. This study provides close monitoring to individuals at risk for developing type 1 diabetes. Individuals who qualify may be offered an opportunity to participate in a prevention study.
Who should I call with questions or to schedule an appointment?
Jaime Realsen: 303-724-5645 or Jaime.Realsen@ucdenver.edu
Vicky Gage: 303-724-6766 or Victoria.Gage@ucdenver.edu
TrialNet website: http://www.diabetestrialnet.org