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University of Colorado Denver

 

Marci Sontag, PhD 

Associate Professor, MPH Concentration Director


Research Interests:
  • Newborn Screening
  • Perinatal Epidemiology
  • Bronchopulmonary Dysplasia
  • The Microbiome and developement of pediatric pulmonary disease
  • Genetic Epidemiology
  • Reproductive and Perinatal Epidemiology
  • Cystic Fibrosis
  •  Public Health Genetic
  • Genetic Modifiers
  • Courses Taught:
  • EPID 6629: Clinical Epidemiology
  • EPID 6642: Genetics in Public Health
  • EPID 7740: Genetic Epidemiology
  • PUBH 6955: MPH Masters Project
  • Current Research Projects:
     
  • HRSA (MCH):  “NewSTEPs: Newborn Screening Technical assistance and Evaluation Program”  The aims of this project are to develop and maintain a data repository for newborn screening in the United States, provide technical assistance to newborn screening programs, and improve the quality of newborn screening systems and outcomes. 

     

  • NIH (NICHD) “Pilot Newborn Screening Project to prospectively identify and follow infants with Spinal Muscular Atrophy”  The major goal of this project is to explore the ethical and legal issues associated with the use of dried blood spots for research related to newborn screening and to implement a pilot newborn screening study for spinal muscular atrophy to assess the feasibility of a DNA-based assay for homozygous SMN1 deletion to detect infants at risk for development of SMA.

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  • NIH (NHLBI):  “Impaired Angiogenic Signaling in BPD”  The major goal of this project is to identify biomarkers of BPD and genetic variations in VEGF-NO pathway genes that are associated with the development of BPD in prematurely born infants.                               

      

  • GERBER FOUNDATION:  “The Microbiome in Premature Infants at Risk for Bronchopulmonary Dysplasia”  The goal of this project is to serially evaluate the airway microbiome from birth through the first weeks of life in mechanically ventilated preterm infants. We will examine how the early acquisition of bacteria, including potentially novel pathogens, interacts with the developing immune response to alter lung development and the risk of bronchopulmonary dysplasia (BPD), the chronic lung disease of prematurity.

     
  • Education:
  • University of Denver, BS, Mathematics, 1994
  • University of Colorado Denver, MS, Biometrics, 1996
  • University of Colorado Denver, PhD, Analytical Health Sciences, Epidemiology, 2004
  • University of Colorado Denver

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