Dr. Ramsdell's research involves the use of biochemical approaches for the study of toxic chemical exposures and effects. Processes responsible for the bioactivation and detoxification of toxic chemicals as well as the biochemical changes caused by toxic chemical exposure are among his interests. A major research area is the use of biochemical end points as biomarkers of exposure and effects of environmental toxicants. Recent and ongoing projects include field and laboratory biomarker studies of wildlife species (mammalian, avian, amphibian) and humans potentially exposed to environmental contaminants. Another area of research active in Dr. Ramsdell's labs is the use of planaria, an invertebrate flatworm, as a model for toxicology studies.