Dr. Bauer is an assistant professor in Department of Environmental and Occupational Health at the Colorado School of Public Health. She is a toxicologist that is interested in two central focus areas that are relevant to human health concerns, one for environmental research and one for basic cancer research, both of which generally focus on the mechanisms driving lung tumorigenesis and the associated inflammation. Prior to coming to Colorado, she was a faculty member in the Department of Pathobiology and Center for Integrative Toxicology at Michigan State University and maintained her own environmental and basic cancer laboratory. Her post-doctoral training was at the National Institute for Environmental Health Sciences in the Laboratory of Respiratory Biology with Dr. Steven Kleeberger on environmental genetics. She received her Ph.D. from the University of Colorado Health Sciences Center in Pharmacology in Dr. Al Malkinson’s laboratory and her B.S. in biochemistry from Pennsylvania State University. She has on-going research studies with collaborators at NIEHS, M.D. Anderson, Michigan State University, Ruhr-University, Bochum, Germany, and Masaryk University, Brno, Czech Republic.
- Environmental and occupational lung carcinogenesis, specifically tumor promotion
- a. E.g. polycyclic aromatic hydrocarbons (PAHs), nanotubes, particles, and heavy metals
- Innate immune system in mouse and human lung inflammation and tumorigenesis
- Innate immune system in ozone-induced lung injury and inflammation
- Novel therapeutic approaches for non-small cell lung cancer
- Osgood, R.S., Upham, B.L., Hill, T, Helms, K.L., Velmurugan, K, Babica, P., Bauer, A.K. 2013. Polycyclic aromatic hydrocarbon-induced signaling events relevant to inflammation and tumorigenesis in lung cells are dependent on molecular structure. PLOS ONE, 3;8(6):e65150. doi:10.1371/journal.pone.0065150.
- Bauer, A.K., *Xiong, K., Velmurugan, K., *Alexander, C.M., *Xiong, J., and *Brooks, R. 2016 Epiregulin is required for lung tumor promotion in a two-stage carcinogenesis model. Molecular Carcinogenesis, Feb 19. doi: 10.1002/mc.22475.
- Alexander, C.M., Xiong, K., Velmurugan, K., Osgood, R.S., Xiong, J., Bauer, A.K. 2016 Differential innate immune cell signatures and effects regulated by toll-like receptor 4 during murine lung tumor promotion. Experimental Lung Research, Apr; 42(3):154-73.
- Bayram, H., Bauer, A.K., Abdalati, W., Carlsten, C., Pinkerton, K.E., Thurston, GD, Balmes, J.R., Takaro, T.K. 2016 Environment, Global Climate Change, and Cardiopulmonary Health American Journal of Respiratory and Critical Care Medicine 21 Sep as DOI: 1164/rccm.201604-0687PP.
- Osgood, R.S., Upham, B.L., Bushel, P., Velmurugan, K., Xiong, K., Bauer, A.K. 2017 Secondhand smoke-prevalent polycyclic aromatic hydrocarbon binary mixtureinduced specific mitogenic and pro-inflammatory cell signaling events in lung epithelial cells. (Toxicological Sciences Jan 30. doi: 10.1093/toxsci/kfx027. [Epub ahead of print].
- EHOH 6616: Environmental and Occupational Toxicology
- EHOH 7631: Survey of Environmental & Occupational Health Methods
- EHOH 7632: Advanced Field Methods in Environmental & Occupational Health