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Curriculum

Training Goals

Training in the Cancer Biology PhD Program is based on six comprehensive training fundamentals that strive to integrate knowledge bases with interrelated skills.

Laboratory based training

Through conduct of laboratory-based research trainees utilize their didactic knowledge base; learn experimental design and hypothesis testing, implementation and problem solving, data interpretation and hypothesis revision, and oral and written communication skills.

Didactic knowledge base

Our coursework provides students with a firm foundation in cancer biology and innovative technologies to enable them to conduct the most relevant and cutting edge research.

Hypothesis driven research

Our training includes a strong emphasis on skill development for hypothesis generation and testing. These skills are emphasized in course work, journal clubs, written and oral communication, clinical exposure and laboratory research.

Clinical relevance

We believe that understanding the patient experience and the clinical relevance of their laboratory research will help students to better focus their research plan and develop more nuanced hypotheses. Many clinical related opportunities are available including clinic shadowing and special topics courses that include options to learn about clinical trial design, drug resistance, drug targeting of cancer subtypes, etc.

Communication skills

Research advances are only achieved if scientific discovery is effectively communicated to the rest of the scientific community and the public. Written and oral presentation skills are developed by presentations in seminars and journal clubs, written research proposals and fellowship applications.

Career and professional development

Opportunities for professional development are available throughout a student’s matriculation. These include strengths and goals evaluation, mentoring by the primary mentor and research advisory committee, exposure to various scientific career paths, and professional networking at scientific meetings.

Program Structure and Milestones

Years 1 and 2

Students take Graduate School and Cancer Biology Program specific courses and do three laboratory rotations. At the completion of the first year students take a preliminary exam and begin their thesis research. The preliminary exam has both a written and oral component and is meant to access critical thinking skills and understanding of key concepts in Cancer Biology.

Graduate School required courses

Foundations of Biomedical Sciences is a 10-credit intensive core course required of all PhD trainees and is taken the first semester of graduate school. Trainees also complete a 1-credit course on the Ethical Conduct of Research.

Cancer Biology required courses

Students begin Cancer Biology specific courses in the spring of year 1. All coursework is typically completed in the first two years.

  • CANB 7600 Cancer Biology: This 3-credit course focuses on molecular mechanisms that underlie cancer initiation and pathogenesis. This course is coupled with “Cancer Biology Journal Club” where students read papers on topics presented in CANB 7600.
  • CANB 7610/7611 Pathobiology of Cancer: This 2-credit “hands-on” course is designed to familiarize students with cancer in different organ systems, tumor nomenclature, and micro and gross tumor pathology.
  • CANB 7613 Cancer Biology Journal Club: Students register for Journal Club (1-credit) for 6 semesters, but are encouraged to participate during their entire graduate studies.
  • CANB 7680 Hypothesis Development and Experimental Design: This 3-credit course includes writing an NIH style grant proposal, and peer and faculty critiques in a “mock study section” format.
  • BIOS 6606 Biostatistics: This 3-credit course is taught by our biostatistics faculty and focuses on basic principles of statistics and applications for biomedical research.
  • Electives: Students choose a minimum of one 3-credit elective from a selection of course offerings; popular courses include Receptors and Cell Signaling, Immunology, Tissue Biology and Disease, Histophysiology and Practical Bioinformatics. In addition, 1-credit Special Topics courses are also offered in the spring and focus on cutting–edge technologies and rapidly evolving areas of interest in cancer biology.
Year 3

In the fall of their third year students take their Comprehensive exam which consists of a written document in the format of an NIH application and an oral exam. Questions in the oral exam are meant to probe depth of knowledge and critical thinking. Successful completion of the written and oral exam results in admission to candidacy.

Years 4-5

Students continue their thesis research, have committee meetings every 6 months, prepare manuscripts, and write and defend their thesis. Average time to graduation is 5.4 years. The program requires one first author publication for graduation, however students typically have 2 or more publications.

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