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Department of Orthopedics

Department of Orthopedics
 

Research Opportunities

Orthopedic Surgery Interest Group


​​Below you will find research opportunities listed in REDCap that are currently open for students to participate in. Please browse each one of the  divisional tabs and click on the title of the study to submit an inquiry. Each submission will be evaluated and you will be contacted when matched. For more information on research studies, please contact Frank Scott, MD.

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​Title of Study ​Principal Investig​ator ​Description
 
Karen King, PhD. ​Joint tissues (cartilage, bone, synovial fluid) and blood serum are collected from arthroplasty surgery of patients with and patients without diabetes. These tissues are then analyzed in the laboratory.​

Medial meniscal destabilization (DMM) model of osteoarthritis Karen King, PhD.
​In this study, molecular mechanisms in the development and progression of osteoarthritis (OA) are studied. This includes the use of a validated mouse model for the induction of OA. Since age is a strong risk factor for OA, a range of ages is studied. Since diabetes mellitus (DM) may be a risk factor for OA, mice with DM are also studied.To test mechanistic hypotheses, some of the mice in this study have genetic modifications.​
 
​Bone repair in the diabetic environment Karen King, PhD.
​The goal of this project is to learn how bone quality and bone healing can be improved specifically within the diabetes mellitus environment. Diabetes is strongly associated with reduced bone quality, poor bone healing and higher risk for fracture. We will also test how bone healing can be improved by placing a therapeutic material (drug, etc.) directly into a damaged bone for improving bone health and/or repair.​
 
Karen King, PhD. The ultimate goal of this research is to discover and develop a new intervention to limit inflammation associated with osteoarthritis (OA), the most common joint disorder. This project will look at how inflammation in other diseases such as diabetes mellitus (DM) may be similar on a molecular level to the joint inflammation in OA. Several interventions with clinical potential are tested in this translational research.

Karin Payne, PhD. To develop a dual delivery biomaterial system that can be implanted into the growth plate injury site where it would first release factors that would promote the recruitment of stem cells to the injured site and then release factors that would encourage the cells to form cartilage tissue rather than bone tissue. This would prevent bony bar formation and the significant bone growth problems associated with growth plate injuries.

Revitalization of bone allo​graft with induced pluripotent stem cells for improved spine fusion​ ​Karin Payne, PhD. ​The goal​ of this study is to test whether adding stem cells, such as induced pluripotent stem cells, to the bone graft before implantation into a rat model of spine fusion, will lead to more bone formation than if the graft was implanted alone.​

 
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​Title of Study ​Principal Investig​ator ​Description

​Merribeth Bruntz A comparison of below knee amputation and above knee amputation rates 2000-2012: A retrospective study
Chopart's And Syme's Amputations In An At-Risk Diabetic Population: A 10-Year Review

Merribeth Bruntz
​Chopart's And Syme's Amputations In An At-Risk Diabetic Population: A 10-Year Review.
 
​Transmetatarsal amputation success rates: A retrospective study Merribeth Bruntz
​Transmetatarsal amputation success rates: A retrospective study.
 
Merribeth Bruntz Use of pulse lavage versus gravity lavage in operative management of diabetic foot infections.
 
​Title of Study ​Principal Investigator ​Description​
 
Frank Scott, MD
 
Frank Scott, MD
 
Frank Scott, MD
​Retrospective Study of Diabetes, Carpal Tunnel Syndrome, and Trigger Finger Syndrome Frank Scott, MD ​Retrospective study to determine whether there is a significant association between patients with Type II diabetes mellitus who also have carpal tunnel syndrome or trigger finger syndrome.

 
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​Title of Study ​Principal Investig​ator ​Description

Michael Dayton, MD Early to Intermediate Results of Metal-On-Metal Hip Resurfacing - A Retrospective Analysis.
A Retrospective Review Of Total Hip And Total Knee Arthroplasty​

Eric Hammerberg
A Retrospective Review Of Total Hip And Total Knee Arthroplasty.
​Decision Quality for Total Hip and Knee Arthroplasty Patients in a Safety Net Hospital

Eric Hammerberg
Decision Quality for Total Hip and Knee Arthroplasty Patients in a Safety Net Hospital. 
 
Eric Hammerberg Effect of Socio-demographic Factors on Surgical Consultation among Patients with Osteoarthritic Knee Pain​.
Eric Hammerberg
A Multi-Centre Randomized Trial Comparing Sliding Hip Screws and Cancellous Screws on Revision Surgery Rates and Quality of Life in the Treatment of Femoral Neck Fractures

Interrupted Suture vs. Running Suture For Wound Closure Following Primary Total Knee Arthroplasy

Eric Hammerberg
Interrupted Suture vs. Running Suture For Wound Closure Following Primary Total Knee Arthroplasy
​Prospective Post Market Clinical Follow-Up Study of the Continuum Metal on Polyethylene Acetabular System

Eric Hammerberg ​Prospective Post Market Clinical Follow-Up Study of the Continuum Metal on Polyethylene Acetabular System
 
​Title of Study ​Principal Investigator ​Description​
 
David Hak, MD ​Implementation of a Registry on Bone Infection to Improve Patient Outcomes and Research Efforts.
 
Cyril Mauffrey, MD ​HIV and Orthopaedic Polytrauma, a Retrospective Review.

Cecelia Pascal-Garrido ​Viability of Chondral Flaps of the Hip in Patients with CAM Femoroacetabular Impingement.
Tumor Database​

Bennie Lindeque, MD Tumor database.
​Multicenter Prospective Cohort Study: Operative & Non-Operative Treatment For Extra-Articular Scapula Fractures

​Phillip Stahel, MD​ ​Multicenter Prospective Cohort Study: Operative & Non-Operative Treatment For Extra-Articular Scapula Fractures