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University of Colorado Women's Reproductive Health Research Career Development Center

(UC-WRHR Center)



The University of Colorado is home to world class health care and research programs in women’s health including reproductive disorders of adults and adolescents, perinatal/fetal biology, cancer biology, obesity, contraception, endocrinology, infectious disease and mental health disorders related to pregnancy.  The goal of the UC-WRHR Center is to enable obstetricians and gynecologists to become successful physician scientists by providing outstanding research training and career development in these areas. 

The UC-WRHR Center has an outstanding group of mentors from basic science and clinical departments within the University of Colorado School of Medicine and from the Colorado School of Public Health to provide guidance for UC-WRHR Scholars.  Our mentors have an excellent record of training physician scientists in basic, clinical and translational research pursuits.  UC-WRHR Center Scholars have access to diverse education and research opportunities including masters and PhD programs offering specialized training in Reproductive Science, Molecular Biology, Public Health and Clinical Science.

In 1999, the University of Colorado, Department of Obstetrics and Gynecology was recognized by NIH with funding to be one of the first Women’s Reproductive Health Research Career Development Centers in the United States.  Funding for the UC-WRHR Center was renewed for the 2005-2010 period and again for the 2010-2015 period. 

The UC-WRHR Center is located at the University of Colorado Anschutz Medical Campus in Aurora Colorado, which is part of the greater Denver metropolitan area.  The campus integrates the Schools of Medicine, Pharmacy and Dental Medicine, the College of Nursing, the School of Public Health​, University of Colorado Hospital and Children’s Hospital Colorado.    

 

  • MD or MD/PhD with completed residency in a US program (applicants with significant research experience will be given priority)
  • No previous NIH independent research awards (R01, R03, or K award)
  • United States citizen or permanent resident with an Alien Registration Card (Green Card)

Qualified individuals interested in the WRHR Scholars program should send the following information to the Program Administrator via email at barb.hughes@ucdenver.edu

·         Brief statement of your research and career plans

·         Curriculum vitae or biosketch.

Individuals selected for candidacy in the UC-WRHR Scholars program and their selected mentor will prepare an application detailing prior research and educational experiences, a concept proposal for a research project in the field of interest (which must be relevant to Women’s Reproductive Health), and a mentoring plan according to the following guidelines:

·         Proposed research plan with Abstract, Hypothesis, Specific Aims and Objectives (2-3 pages)

·         Career development plan, including personal statement and career goals, mentor’s statement, and proposed didactic program (5-6 pages)

·         3 letters of recommendation: One letter must be from the candidate’s current chair, two letters of reference may be from director of residency/fellowship training program, previous mentors or other physician and scientists familiar with the candidate’s qualifications

·         Selected mentor’s name and research focus

·         If the prospective mentor is not among those already approved (see list below), an NIH biosketch, research summary, and list of current and past trainees will be required for review

Potential applicants who cannot determine whether or not a particular faculty member is an appropriate mentor for his/her intended research should contact Barb Hughes (Barb.Hughes@ucdenver.edu) for assistance with the process.  All applications will be reviewed by the UC-WRHR Centers Advisory Committee.

WRHR Scholar positions provide research and salary support at the level of instructor or assistant professor for a minimum of two years and up to five years. Individuals are required to spend a minimum of 75% of full-time professional effort conducting research and research career development.

Nanette Santoro, MD – Principal Investigator

Professor and E. Stuart Taylor Chair of Obstetrics and Gynecology, University of Colorado Anschutz Medical Campus.

Contact Information:

University of Colorado

Anschutz Medical Campus

Mail Stop B-198

12631 East 17th Avenue

Academic Office 1, Room 4010

Aurora, CO 80206

Phone: 303-724-2041

FAX:  303-724-2061

Email:  nanette.santoro@ucdenver.edu

 

James McManaman, PhD – Research Director

Professor and Acting Chief, Section of Basic Reproductive Sciences; Professor Physiology and Biophysics and Graduate Programs in Reproductive Sciences, Molecular Biology and Cells, Stem Cells and Development

Contact Information:

University of Colorado

Anschutz Medical Campus

Mail Stop 8613

12700 East 19th Avenue

RC-2, Room 3013

Phone:  303-724-3500

FAX: 303-724-3512

Email:  jim.mcmanaman@ucdenver.edu

 

Barbara Hughes – Program Assistant

Contact Information:

University of Colorado

Anschutz Medical Campus

Mail Stop 8613

12700 East 19th Avenue

RC-2, P15-3010

Phone:  303-724-3506

FAX: 303-724-3512

Email: Barb.Hughes@ucdenver.edu​

Steve Abman, MD, Professor of Pediatrics; Director, Pediatric Heart Lung Center.  

Steve Anderson, PhD, Professor and Vice Chair of Research, Department of Pathology 

Linda Barbour, MD, Professor, Department of Medicine, Division of Endocrinology

Kian Behbakht, MD, Associate Professor of Obstetrics and Gynecology; Director, Gynecologic Oncology Fellowship Program

Andrew Bradford, PhD.  Associate Professor of Obstetrics and Gynecology, Director PiRS graduate Program

Tim Byers MD MPH,  Professor and Associate Dean for Public Health Practice, Colorado School of Public Health

John C. Cambier, PhD, Professor and Chairman, Integrated Department of Immunology

Robert H. Eckel, MD, Professor of Medicine, Division of Endocrinology, Metabolism and Diabetes , and Division of Cardiology ; Professor of Physiology and Biophysics. 

Heide L. Ford, PhD, Associate Professor of Obstetrics and Gynecology, Division of Basic Reproductive Sciences

Jacob Friedman , PhD, Professor of Pediatrics, Associate Director of the Perinatal Research Center Cell and Molecular Biology Lab .

Henry L. Galan, MD, Professor of Obstetrics and Gynecology; Division Chief, Maternal-Fetal Medicine. 

Arthur Gutierrez-Hartmann, MD, PhD Professor of Medicine/Endocrinology and Metabolism, Director MSTP Program.

William W. Hay, MD, Professor of Pediatrics;  Director, Perinatal Research Center.

Peter M. Henson, DVM., PhD, Professor of Pathology and Medicine, National Jewish Health.

Michael Holers, MD, Professor of Medicine; Chief, Division of Rheumatology. 

Kathryn B. Horwitz, PhD, Distinguished Professor of Medicine; Division of Endocrinology and Metabolism

Madeleine Kane, MD, PhD, Professor of Medicine; Division of Medical Oncology; Medical Director, University of Colorado Clinical Investigations Core

Ross Kedl, PhD, Assistant Professor, Immunology

Anne Lynch, MD, MSPH, Assistant Professor, Obstetrics and Gyencology

James McManaman, PhD, Professor and Acting Chief, Basic Reproductive Sciences, Department of Obstetrics and Gynecology

Jane E-B Reusch MD, Professor of Medicine Denver VA Medical Center

Randy Ross, MD, Professor of Psychiatry

Nanette Santoro, MD, Professor and Chair of Obstetrics and Gynecology

Ann D. Thor, MD, Professor and Chair of Pathology

Margaret E. Wierman, MD, Professor of Medicine, Division of Endocrinology and Metabolism

Current WRHR Scholars-

Laxmi A. Kondapalli, MD MSCE

Dr. Kondapalli received her medical degree from the University of Vermont College of Medicine in 2002 and completed her residency in Obstetrics and Gynecology at Northwestern University in 2006. She remained at Northwestern from 2006-2008 as a post-doctoral research fellow in reproductive biology lab of Teresa K. Woodruff, PhD. She completed her Reproductive Endocrinology and Infertility fellowship and received a Master of Science degree in Clinical Epidemiology at the University of Pennsylvania in 2011. She has been a WRHR Scholar at the University of Colorado since 2011. Dr. Kondapalli's research interests focus on late effects of cancer therapy on gonadal function, fertility preservation methods, and childhood outcomes after assisted reproduction.    Details are on Dr. Kondapalli's Oncofertility website​

Camille Hoffman, MD

Dr. Hoffman received her medical degree from the Medical University of South Carolina in 2003, completed a residency in Obstetrics and Gynecology at University of Miami/Jackson Memorial Hospital in 2007, and completed a fellowship in Maternal Fetal Medicine at University of Colorado in 2010.  Following fellowship, she became a faculty member and WRHR Scholar at the University of Colorado.  Dr. Hoffman's research interests focus on the role of psychosocial and physiologic stress on pregnancy outcomes.  She is evaluating ultrasound and noninvasive biomarkers of stress to assess maternal and child hypothalamic-pituitary-adrenal axis function.

Crystal Adams, MD

Dr. Adams received her MD from the University of Texas Health Science Center San Antonio in 2006. In 2010, she completed her residency in Obstetrics and Gynecology at the University of Texas Southwestern Medical Center – Austin.  This was followed by a one-year fellowship in gynecologic and minimally invasive surgery at Virginia Mason Medical Center in Seattle.  Dr. Adams has been a WRHR scholar and assistant professor at the University of Colorado since 2012. Her research interests are centered on the modulation of gene expression in ovarian malignancy, with a goal to better understand the mechanisms behind cancer cell resistance to chemotherapy and the development of molecularly targeted treatment modalities.


Past WRHR Scholars-

K. Joseph Hurt, MD, PhD (2010-2012)

Dr. Hurt graduated with MD and PhD degrees from the Johns Hopkins School of Medicine.  He completed his residency in Gynecology & Obstetrics also at Hopkins in 2009, then spent one year as a research fellow in the neuro-urology research laboratory of the Hopkins Brady Urological Institute.  Dr. Hurt is currently an Assistant Professor and Fellow in Maternal Fetal Medicne at the University of Colorado.   His laboratory works to understand the role of the gasotransmitters nitric oxide and hydrogen sulfide in regulating myometrial quiescence and parturition, with the goal of developing novel therapies to prevent preterm birth.

Irina Dimitrova, MD (2005-2009)

Dr. Dimitrova received her MD from Sophia University, Bulgaria in 2001 and completed her residency in Obstetrics and Gynecology, Oakwood Medical Center, Dearborn, MI.   She was accepted into the Gynecologic Oncology Fellowship at the University of Colorado.   Her research interests focus on microRNAs  in  ovarian cancer and microarray analysis to identify mechanisms underlying the pathogenesis of uterine leiomyosarcomas and leiomyomata. 

Monique A. Spillman, MD, PhD (2006-2010)

Dr. Spillman received and MD/PhD from University of Texas, Soutwestern in 1999 and completed her residency at Brigham and Womens’ Boston (2003).  She was Gynecologic Oncology at Duke University from 2003 – 2006.  She is currently an Assistant Professor in Genecologioc Oncology at the University of Colorado School of Medicine . Dr. Spillman’s research interests focus on understanding hormonal regulation of human ovarian cancer using mouse xenograft models.

Virginia D. Winn, MD, PhD (2007-2010)

Dr. Winn received an MD,PhD, from the University of Rochester in 1996 and completed her residency in Obstetrics and Gynecology at the University of San Francisco in 2000.  She was an MFM Fellow at UCSF from 2000-2003 and an Instructor/Adjunct Professor from 2003-2006.  She has been a WRHR Scholar at the University of Colorado since 2007.  Dr. Winn’s research interests are to understand the genes and molecular pathways modulated during the formation and function of the maternal-fetal interface.  She is specifically interested in how these pathways contribute to obstetrical complications such as preeclampsia. 

Lorraine Dugoff, MD​ (2006-2008)

Dr.  Dugoff received her MD from Georgetown University School of Medicine in 1989 and completed fellowships in Maternal Fetal Medicine and Clinincal Genetics and the Univesrity of Coloradio helath Sciences Center. She is currently is an Associate Professor, in the Department of Obstetrics and Gynecology, Perelman School of Medicine, Univesrity of Pennsylvania.    Her research focuses on the identification of maternal serum markers for screening and prediction of preeclampsia, fetal chromosomal anomalies and perinatal birth defects.   

Henry Galan, MD (2000-2003)

Dr. Galan is Professor and Chief of the Maternal Fetal Medicine Section of the Department of Obstetrics and Gynecology, University of Colorado Anschutz Medical Campus.  Dr. Galan’s research focuses on the hemodynamics of interuterine growth restriction. 

Ra

dika Gogoi (nee Ghatge), MD, PhD (2000-2005)

Dr.  Gogoi is a Clinical Assistant Professor at Lankenau Institute for Medical Research and Lankenau Hospital, Wynnewood Pennsylvania.   Following completion of her WRHR Fellowship she completed a fellowship in Gynecologic Oncology at New York University.  Her research interests are HPV promoter for targetted cell death of HPV infected cervical cancer cells and the role of estrogens role in the development of pulmonary mycobacterium avium complex.