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Oncology Research Information Exchange Network




Total Cancer Care

Total Cancer Care®is a unique research study designed to bring cancer treatment to a new level. By tracking and studying data from participants, it is changing the way doctors prevent, detect and treat cancer. The Oncology Research Information Exchange Network (ORIEN) was created as a network of respected cancer centers that will share this information, therefore expanding the tools available to oncologists in a way that’s never been done.

The study is designed to:

·      Evaluate the long­-term effects of different cancers, treatment choices and lifestyle

·      Give physicians a better understanding of patient outcomes and treatment options

·      Help patients find clinical trials that reflect the details of their diagnosis

·      Develop a molecular database that can serve as a resource for future research

More than 273,000 patients, across all ORIEN Members in the United States, have enrolled in the study since it was launched in 2006. Each new participant brings us one step closer to our goal of finding a cure for cancer.  Learn more about Total Cancer Care®. To sign up for the study, please email orien@ucdenver.edu​​


Oncology Research Information Exchange Network (ORIEN)

The Oncology Research Information Exchange Network (ORIEN) is a unique research partnership among North America’s top cancer centers that recognize collaboration and access to data are the keys to cancer discovery. Through ORIEN, founders Moffitt Cancer Center in Tampa, Florida, and The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute in Columbus leverage multiple data sources and match patients to targeted treatments.ORIEN Members are supported by M2Gen, a subsidiary of Moffitt Cancer Center.  M2Gen is responsible for the tissue and data collection from patients enrolled on the Total Cancer Care protocol and the related Total Cancer Care database.


ORIEN partners utilize Total Cancer Care® which provides a standard system for tracking patient molecular, clinical and epidemiological data and follows the patient throughout his or her lifetime. Partners have access to one of the world’s largest clinically annotated cancer tissue repositories and data from more than 240,000 patients who have consented to the donation for research. 


ORIEN’s mission: Accelerating cancer discovery and delivering hope through collaborative learning and partnerships. Learn more at www.oriencancer.org.